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Agilent K6460S Clinical Edition TQ LC/MS System

Agilent this week launched the K6460S Clinical Edition TQ LC/MS system, a triple quadrupole liquid chromatography/mass spectrometry system designed to improve in vitro diagnostic workflows in clinical labs. The system is listed as a Class I medical device with the US Food and Drug Administration and includes the clinical edition of Agilent MassHunter software to enable an easy and intuitive submission-to-reporting workflow. TQ LC/MS increases the specificity, selectivity, and accuracy of many clinical diagnostic assays compared to traditional binding assays, Agilent noted in a statement. The platform also received approval from China's National Medical Products Administration in January.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.