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Agena UltraSeek Lung and Colon Panels

Agena Bioscience has launched the UltraSeek Lung and Colon panels for the detection of somatic mutations from lung and colon cancers. The panels enable mutation profiling of circulating tumor DNA and circulating tumor cells from plasma and solid tumor tissue. They also target mutations of known significance in BRAF, EGFR, ERBB2, KRAS, NRAS, and PIK3CA genes. The panels can work with DNA extracted from a single 10 mL blood draw and can detect mutations as low as 0.1 percent minor allele frequency, the company said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.