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Adaptive Biotechnologies, Microsoft ImmuneCode COVID-19 Database

Adaptive Biotechnologies and Microsoft have launched ImmuneCode, an open database related to the immune response of individuals with COVID-19. The deidentified data contains information on T cells shown to recognize antigens of the SARS-CoV-2 virus, obtained from blood samples. It provides a population-level view into the adaptive immune response; samples have been drawn from geographically and ethnically diverse patients as part of Adaptive's ImmuneRace study. The data will be freely available to any researcher, public health official, or organization around the world, Adaptive said.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.