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10x Genomics Visium Spatial Gene Expression Solution

10x Genomics has launched its Visium Spatial Gene Expression solution. The assay provides researchers the ability to map where gene activity is occurring in a tissue specimen, with whole-transcriptome analysis of up to hundreds of thousands of cells on a tissue section.

Visium builds on earlier products from Spatial Transcriptomics, which 10x acquired in 2018, offering five times more spots within a capture area while reducing the time it takes from three days to one day.

Visium also includes turn-key software and requires access to an optical microscope.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.