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10x Genomics Single Cell Mouse Immune Profiling Solution

10x Genomics has launched the Single Cell Mouse Immune Profiling Solution for characterizing gene expression and paired receptor sequences of T cell and B cells in mouse models of disease. The product enables full-length receptor sequencing and unbiased clonotype analysis of T-cell and B-cell populations through paired heterodimeric receptor gene sequencing, according to the company. It includes a software suite to analyze and visualize large single-cell experiments quickly.

The Scan

Nucleotide Base Detected on Near-Earth Asteroid

Among other intriguing compounds, researchers find the nucleotide uracil, a component of RNA sequences, in samples collected from the near-Earth asteroid Ryugu, as they report in Nature Communications.

Clinical Trial Participants, Investigators Point to Importance of Clinical Trial Results Reporting in Canadian Study

Public reporting on clinical trial results is crucial, according to qualitative interviews with clinical trial participants, investigators, and organizers from three provinces appearing in BMJ Open.

Old Order Amish Analysis Highlights Autozygosity, Potential Ties to Blood Measures

Researchers in BMC Genomics see larger and more frequent runs-of-homozygosity in Old Order Amish participants, though only regional autozygosity coincided with two blood-based measures.

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.