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10X Genomics GemCode Platform

10X Genomics has started shipping the GemCode platform for generating long range genomic information from short read sequencing data. The platform consists of instrumentation, reagents, and software and generates so-called Linked-Reads that deliver haplotype phasing, structural variation, and other genomic information. GemCode, which requires 1 nanogram of input DNA, partitions arbitrarily long DNA molecules and prepares multiple barcoded sequencing libraries in parallel. 10X Genomics previewed the product earlier this year at the Advances in Genome Biology and Technology conference.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.