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10X Genomics GemCode Platform

10X Genomics has started shipping the GemCode platform for generating long range genomic information from short read sequencing data. The platform consists of instrumentation, reagents, and software and generates so-called Linked-Reads that deliver haplotype phasing, structural variation, and other genomic information. GemCode, which requires 1 nanogram of input DNA, partitions arbitrarily long DNA molecules and prepares multiple barcoded sequencing libraries in parallel. 10X Genomics previewed the product earlier this year at the Advances in Genome Biology and Technology conference.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.