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10x Genomics Chromium System

10x Genomics has launched a new Chromium System, an upgrade for existing short-read sequencers. It unlocks critical long-range genomics and cell-by-cell gene expression information, the firm said. The system supports the following applications:

  • Chromium Single Cell 3', which performs deep profiling of complex cell populations with high-throughput digital gene expression on a cell-by-cell basis.
  • Chromium Genome, which provides long-range information on a genome-wide scale, enabling identification of critical variants in heritable disorders and discovery of key alterations in cancer.
  • Chromium Exome, which provides long-range information for phasing structural variant detection and copy number determination, giving researchers access to low-complexity and repetitive regions previously missed with short-read sequencing.
  • The Supernova Assembler, which opens the door to low-cost, everyday diploid de novo assemblies by unlocking sample-specific sequence and produces diploid genome structure.
The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more