10x Genomics Chromium System

10x Genomics has launched a new Chromium System, an upgrade for existing short-read sequencers. It unlocks critical long-range genomics and cell-by-cell gene expression information, the firm said. The system supports the following applications:

• Chromium Single Cell 3', which performs deep profiling of complex cell populations with high-throughput digital gene expression on a cell-by-cell basis.
• Chromium Genome, which provides long-range information on a genome-wide scale, enabling identification of critical variants in heritable disorders and discovery of key alterations in cancer.
• Chromium Exome, which provides long-range information for phasing structural variant detection and copy number determination, giving researchers access to low-complexity and repetitive regions previously missed with short-read sequencing.
• The Supernova Assembler, which opens the door to low-cost, everyday diploid de novo assemblies by unlocking sample-specific sequence and produces diploid genome structure.