10x Genomics Chromium Single-Cell CNV Solution
10x Genomics has launched the Chromium Single-Cell CNV Solution, a scalable technology for rapid and parallel profiling of single-cell genomes. The solution is built on the firm's technology for generating cell beads and gel beads, and enables preparation of hundreds to thousands of single cells for CNV profiling within minutes on either the Chromium Controller or the Chromium Single-Cell Controller. It profiles the genomes of individual cells and can be used for applications such as revealing tumor heterogeneity, characterizing somatic mosaicism of neurons, and authenticating cell line identity and clonal purity. The product also further examines the clonal structure of cancer samples, including spatial distribution across tumor slices and longitudinal changes.