Ares Genetics, an OpGen subsidiary, has commercially launched ARESCloud, a web application aimed at accelerating the analysis of sequenced clinical isolates. The software fully auotmates data processing, from raw sequence data to report, and offers insights into epidemiologically and etiologically relevant information including pathogen identity, genotype, virulence, plasmids, and antimicrobial resistance. The news software also features tools for comparative and outbreak analysis. Under a simple subscription model users can access ARESdb, a proprietary knowledgebase containing comprehensive information on genetic and mutational AMR markers as well as advanced machine-learning models for the prediction of antibiograms directly from genomic data, the company said.
Promega has launched the ProDye Terminator Sequencing System, a Sanger sequencing chemistry that can be implemented on any capillary electrophoresis instrument, including Promega's own benchtop Spectrum Compact CE System. The new chemistry uses a proprietary thermostable DNA polymerase and the same dyes contained in Thermo Fisher Scientific's BigDye Terminator V3.1 Cycle Sequencing Kit.
Purigen Biosystems has launched the Ionic Tissue to Pure DNA Kit. It allows users of the Ionic Purification System, a benchtop instrument for the automated extraction of nucleic acids, to obtain increased yields of high-quality DNA from fresh-frozen biological samples with an automated workflow. The kit consists of six chips and a reagent set with all needed enzymes and buffers to extract DNA from 48 samples.
Takara Bio USA has launched the Smart-Seq Pro kit for the ICell8 cx single-cell system.
This automated single-cell RNA-seq solution allows researchers to generate full-length transcriptome data from over 1,500 single cells simultaneously, from a wide range of sample types. The kit can generate transcriptome data from eight at samples at a time.
PerkinElmer and Honeycomb Biotechnologies have commercially launched the HIVE scRNAseq Solution for single-cell isolation analysis. The product is a portable, handheld device for the capture, storage, and RNA-seq library preparation of a diverse range of cell types, including fragile and labile cells such as granulocytes, nephrons, hepatocytes, and neurons, the companies said. HIVE integrates sample capture and preservation into a single-use device, making it possible to collect samples from multiple sites and maintain sample integrity during storage, shipping, and processing from a central testing lab, which is particularly important for multi-center studies, the companies said. Cells are gently loaded by gravity in volumes up to 4 mL, enabling capture of fragile cell types and processing of sparse samples such as fine needle aspirates, cytobrushes, and flow-sorted cells.
EliTechGroup has launched a CE-IVD marked, standalone, sample-to-result RT-PCR testing system called the Elite BeGenius. The system boasts a compact footprint, ease-of-use, and total automation, and performs up to 24 tests per run.
Lybe Scientific, a startup commercializing nanoparticle-based technology developed at the Norwegian University of Science and Technology, has launched its first product with CE marking, the NAxtra nucleic acid extraction kit, a magnetic bead-based technology intended for viral RNA extraction from human nasopharyngeal and/or oropharyngeal swab samples. The kit should be used for the isolation and purification of viral RNA when preparing clinical samples for downstream molecular diagnostics, and is intended for use by clinical laboratory personnel specifically instructed and trained in magnetic bead-based nucleic acid purification and in vitro diagnostic procedures, the company said.
CareDx has launched AlloSure Lung. AlloSure, the company's donor-derived cell-free DNA test for noninvasive transplant surveillance, is available for assessing kidney and heart transplantation. It will now also be available for use in lung transplantation.
NanoString Technologies has announced the launch of an antibody drug conjugate (ADC) panel for its nCounter platform. The new panel offers customizable content to help evaluate ADC's throughout discovery, pre-clinical, and clinical studies. It can profile 770 genes relevant to ADC development, including tumor targeting and antigen expression, internalization, payload release, drug mechanism of action, target cell death, immunogenic cell death, and mechanisms of resistance.
Sophia Genetics has introduced version 3 of its Clinical Exome Solution application. The new release features a capture-based target enrichment kit as well as what the company said is "enhanced" probe design for better detection of Mendelian diseases from within the entire mitochondrial genome and noncoding variants in 280 specific genomic locations.