Close Menu

Variant Review Scientist

Organization
University of Washington Medical Center
Job Location
1959 NE Pacific St
Seattle, WA 98002
United States
Benefits

This position provides opportunities to work in a fast-paced, challenging, diverse and rewarding environment.  As an employee you will enjoy generous benefits and work/life programs.  For detailed information on Benefits for this position, visit: http://hr.uw.edu/benefits/wp-content/uploads/sites/3/2017/06/BAAG-Acad-P...


Job Description

Our LABORATORY MEDICINE AND PATHOLOGY DEPARTMENT has an outstanding full-time position for a Variant Review Scientist.  This individual will review and interpret genetic variants from molecular testing and assist lab directors with interpretation and reporting of exciting new genomic-based diagnostic testing in genetics, with a focus on next-generation sequencing for inherited disorders.  This includes the review of complex genetic panels, exomes, clinical genomes, and other advanced diagnostic testing applied to large research studies supported by the genetics division of Laboratory Medicine, reviewing research genetics testing results, providing expert interpretation, and developing novel methods and techniques to analyze data.

Data Analysis

  • Generates data and responsible for review and interpretation of genomic test results under direction of clinical laboratory directors.       
  • Provide analysis and consultant to physicians and scientists in other departments as needed to guide development, implementation and interpretation of genomic test services.
  • Review patient medical history to determine eligibility for exome NGS testing.
  • Write patient reports for review by genetics, neurology, and other healthcare specialty clients.
  • Interpret data from high complexity genomic techniques including next generation sequencing and arrays.
  • Develop and coordinate data analysis strategies and implementation for large research projects.
  • Develop relationships and independently consult experts in the field to assist with interpretation of challenging variants.

Development and Maintenance

  • Responsible to review genomic data and maintain the active knowledgebase for variant interpretation.
  • Update variant curation strategies, variant scoring process, interpretation process, and reporting process on an ongoing basis.
  • Develop expertise in interpreting genetic data from open source and proprietary analysis softwares and databases.
  • Design of tools to assist in more efficient variant review for the variant review scientist and affiliated faculty.

Scholarly activities

  • Responsible for extensive literature review and provide consult, input and collaborates in interdepartmental journal clubs for ongoing education.
  • Responsible to generate, develop, and provide data at client meetings and conferences, when required.
Requirements

Requirements
Master’s Degree  in genetics, genomics, molecular biology, chemistry, biochemistry or related discipline and two to three years of experience.

Equivalent experience substitute for degree requirement.

Additional requirements:

Experience in molecular biology methods and data analysis.

Strong teamwork, interpersonal, and managerial skills.

Strong organizational and documentation skills suitable to a clinical laboratory environment. Demonstrates ability to rapidly distill concise and succinct summaries from complex and potentially contradictory literature sources.

Comfortable using a variety of computational databases to aid in the interpretation of genomic variants.

Ability to work independently. Ability to prioritize and work under tight deadlines.

Excellent verbal and written communication and organizational skills.

Desired Requirements

Ph.D. in genetics, genomics, molecular biology, chemistry, biochemistry or related discipline.

 

 

How to Apply

Please apply directly through the UW Hires job posting at: https://uwhires.admin.washington.edu/eng/candidates/default.cfm?szCatego...

 

About Our Organization

The Department of Laboratory Medicine and Pathology serves as a regional resource for clinical laboratory services required for patient care, research and educational programs in laboratory medicine and pathology. The department now employs 900 people who work at the award-winning University of Washington Medical Center (ranked among the top medical centers in the United States as rated by U.S. News & World Report), Harborview Medical Center (the region's only Level I Trauma center, known for innovations and excellence in trauma care and its centers of emphasis: Trauma, Burn, Neurosciences, AIDS/STD CARER, and mentally- and medically- vulnerable populations.), and many other clinical and research facilities in the area. The University of Washington (UW) is proud to be one of the nation’s premier educational and research institutions. Our people are the most important asset in our pursuit of achieving excellence in education, research, and community service. Our staff not only enjoys outstanding benefits and professional growth opportunities, but also an environment noted for diversity, community involvement, intellectual excitement and natural beauty. 

A new report finds that women, especially women of color, are missing among the high-earners at research universities in the US, the Chronicle of Higher Education writes. 

Researcher-parents, especially mothers of small children, have lost research time during the COVID-19 pandemic, according to the Chronicle of Higher Education.

Inside Higher Ed reports that the preprint site medRxiv has taken off with the COVID-19 pandemic.

Inside Higher Ed reports some university professors are pushing back against plans for increased numbers of in-person classes for next semester.