Team Leader – Variation Annotation

Job Location
Wellcome Genome Campus
CB10 1SD
United Kingdom

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. The remuneration package comprises a competitive salary, a comprehensive pension scheme and health insurance, educational and other family related benefits where applicable, as well as financial support for relocation and installation.

We have an informal culture, international working environment and excellent professional development opportunities but one of the really amazing things about us is the concentration of technical and scientific expertise – something you probably won't find anywhere else.

If you've ever visited the campus you'll have experienced first-hand our friendly, collegial and supportive atmosphere, set in the beautiful Cambridgeshire countryside. Our staff also enjoy excellent sports facilities including a gym, a free shuttle bus, an on-site nursery, cafés and restaurant and a library.

Job Description

The European Bioinformatics Institute (EMBL-EBI) seeks a Team Leader to provide visionary leadership of its Variation Annotation Resources.

The Team Leader will lead a newly organised faculty level team consisting of approximately 15 staff members. The team is responsible for the annotation, curation and distribution of variation data from human and other species. This role includes leadership of the recently launched European Variation Archive, and management of the EBI portion of the NHGRI-EBI GWAS catalog in collaboration with the Samples Phenotypes and Ontologies Team. Other responsibilities include the Ensembl variation database and several efforts to translate EBI resources for more effective use in clinical research or diagnostic situations.

The team leader will be expected to work closely with other components of the Ensembl project as well as the European Genome-phenome Archive (EGA) and European Nucleotide Archive (ENA) within EBI's newly created Molecular Sequence Archive Cluster. He/she will also form external collaborations and raise funds via competitive peer-reviewed grants to supplement core funding allocated for the team leader position, staff members and computational infrastructure. A key task of the team will be the continued development of EBI's high-value resources designed to serve as a platform for research into molecular medicine, disease and connections between genome variation and phenotype for human and other species.

The team leader will be expected to develop connections with appropriate European health care and research organisations and worldwide partners such as the International Rare Disease Research Consortium (IRDiRC), the Global Alliance for Genomics and Health (GA4GH) and the US National Center for Biotechnology Information (NCBI).


The ideal candidate will hold an MD or a PhD in Genetics, Molecular Biology, Computer Science or other relevant field with postdoctoral experience. Applicants with considerable demonstrated experience of team leadership in the specific fields will also be considered. All candidates are required to have practical with bioinformatics and genome-wide computational analysis, preferably in a production environment. It would be a distinct advantage to have personnel and project management experience and demonstrated potential of successful application and management of external grants, although this is not essential.

Excellent English, both written and oral, and interpersonal skills are essential.

How to Apply

Please apply online through

About Our Organization

EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL) and it is a world-leading bioinformatics centre providing biological data to the scientific community with expertise in data storage, analysis and representation. EMBL-EBI provides freely available data from life science experiments, performs basic research in computational biology and offers an extensive user training programme, supporting researchers in academic and industry. We have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute.

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