Systems Geneticist

Broad Institute
Job Location
Cambridge, MA
Job Description

The Broad Institute of MIT and Harvard is the world’s leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.

Founded in 2004 by Eric Lander and philanthropists Eli and Edythe L. Broad, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning more than a hundred private and public institutions in more than 40 countries worldwide.

A research scientist I position focused on systems genetics is available at the Broad Institute. This position is a rare opportunity to be part of a dynamic team consisting of experts in biochemistry, computational biology, and clinical medicine focused on the discovery of therapeutics that target energy metabolism. We are seeking a highly motivated research scientist with a strong background in the application of high-throughput genetic screening approaches to understand biological systems to join our multi-disciplinary drug discovery program.

We are looking for an enthusiastic and organized individual who can thrive in a fast-paced environment. Technical skill, attention to detail, and excellent communication skills are a must. There will be ample opportunities for co-authorship on high-impact papers.

• Develop novel screening assays to study energy metabolism
• Implement high-throughput genetic screens using pooled CRISPR and cDNA over-expression libraries
• Plan and execute projects and experiments independently, identifying and resolving technical and methodological problems as they arise
• Attend weekly team meetings to present results, ensuring that projects support current team goals
• Train, supervise, or mentor junior group members as needed

• Ph.D. in biomedical research, with 0+ year of expertise in cell and molecular biology, as well as high-throughput genetic screens
• Strong record of research publications and high profile scientific presentations
• Demonstrated ability to develop and shift plans to adjust to rapidly changing scientific priorities and technologies
• Excellent communication (both in writing and presenting), analytical, and interpersonal skills
• Outstanding organization and time management skills
• Ability to build excellent working relationships and foster collaboration in a team environment

EOE/Minorities/Females/Protected Veterans/Disabilities

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