Sr. Scientist - Oncology Diagnostics

Job Location
3595 John Hopkins Court
San Diego, CA 92121
competitive salary, bonus, equity
Job Description

As a member of the R&D Diagnostics Development team, the Sr. Scientist will plan and execute assay development projects utilizing target enrichment, amplification approaches and next-generation sequencing.  The ideal candidate will have extensive knowledge of biochemistry and molecular biology and a proven track record in development of novel nucleic acid based assays. Previous experience managing research associates is preferred. Technical project leadership experience is desired.  This is an exciting opportunity to be part of a dynamic R&D team and have the opportunity to work on the development of cutting edge diagnostics.



  • Create and optimize novel diagnostic assays
  • Develop next generation sequencing assays and perform data analysis/interpretation
  • Develop target enrichment approaches utilizing multiplex PCR and/or capture methods
  • Conceive and design model systems for proof-of-concept studies
  • Design and execute appropriate analytical verification studies
  • Document all work in the form of laboratory notebook, study reports, summary reports and presentations
  • Present data clearly and concisely at departmental meetings and project meetings
  • Participate and present findings at conferences
  • Publish scientifically relevant data in peer reviewed journals
  • Participate in the development of patent applications, if applicable
  • Independently and/or collaboratively conceive initiate and apply for the acceptance of new projects
  • PhD in Molecular Biology / Biochemistry or a related field
  • 6 - 8 years’ industrial experience in an applied research and/or development environment
  • Experience with creation and optimization of next generation sequencing-based assays
  • Experience with targeted NGS enrichment technologies
  • Experience with multiplex assay design for genomic applications
  • Strong background in data analysis using statistical software packages including R or JMP
  • Experience with prenatal, oncology and/or infectious disease assay development preferred
  • Management experience a plus

Sequenom is an EOE - Minority/Female/Disability/Vets

 To apply, please visit:

About Our Organization

Sequenom Laboratories, a wholly-owned subsidiary of Sequenom, Inc., is a CAP accredited and CLIA-certified molecular diagnostics laboratory, dedicated to the development and commercialization of laboratory-developed tests (LDTs) for prenatal diseases and conditions. Sequenom holds or has access to intellectual property for noninvasive prenatal testing using circulating cell-free fetal nucleic acids.


As a life sciences company, Sequenom (NASDAQ: SQNM) has a guiding vision: To enable healthier lives as the premier provider of innovative genetic information with an exceptional customer experience
What makes this vision a reality? Our deep commitment to "Quality of Science." For us, only the highest quality is acceptable. Sequenom team members thrive in a "science first" environment where ideas and innovation are part of daily life. This is your opportunity to work on cutting-edge science that is revolutionizing patient care.

Our innovation-driven culture means life at Sequenom is fast-paced, dynamic, and fun with rewarding benefits and performance rewards. With a clear vision for the future, all employees have the opportunity to make a difference and are encouraged to share new ideas. We foster a collaborative work environment and encourage curiosity at all levels.  Our corporate headquarters is located in the heart of San Diego’s life sciences community, less than a mile from the beach.

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