Sr. Scientist, Oncology Assay Innovation | GenomeWeb

Sr. Scientist, Oncology Assay Innovation

Roche Sequencing
Job Location
Pleasanton, CA
Job Description


  • Designs, plans and executes assigned research and/or development-related experiments/projects utilizing established and innovative procedures.  

  • Makes recommendations, and when appropriate, acts independently to resolve scientific problems encountered during experimental procedures to improve productivity of results.  

  • Ensures activities are consistent with project critical path, and responds appropriately to changing priorities.   

  • Accurately and consistently records experimental methods, materials and results in electronic laboratory notebooks.

  • Analyzes data, evaluates results, forms conclusions and implements/documents process improvements.  Integrates previous and current results to determine next experimental steps and the impact of long-range project goals.

  • Participates in critical decision making that will impact project team(s) and/or broader organization. Inappropriate decisions may cause a delay in operations, a financial expense and/or customer dissatisfactions.

  • Troubleshoots and resolves difficult problems in creative ways by taking a new perspective on existing solutions, exploring and implementing new concepts and methodologies.

  • Presents findings at group or departmental meetings.  

  • Applies advanced technical writing skills to produce reports and documents.  

  • May assist in preparing summaries, memos, internal reports, presentations, manuscripts, etc.

  • Serves as a resource to other departments (e.g., Manufacturing/Operations, Quality, Marketing, Regulatory Affairs, Clinical Studies, and International Technical Services), provides timely response and follow-ups.  

  • Participates in the expeditious transfer of products and technologies by providing scientific knowledge and assistance



  • Must have PhD in Biological/Life Sciences, Chemistry, Biochemistry or related field.

  • Must have at least 5 years of experience (academic or industry) including direct experience with NGS library preparation, targeted enrichment, and assay development.



  • Direct experience with nucleic acid (NA) based technologies, including NA extractions from tissue and blood samples, designing and optimizing primers and probes for multiplex PCR, real-time PCR and RT-PCR assays.  

  • Experience relevant to the assay development process.

  • Direct experience with NGS library prep, target enrichment, and assay development.

  • NGS data analysis experience is a plus.  

  • Basic understanding and knowledge of cancer biology is a plus.

  • Desire and drive to work on a fast-paced and highly collaborative team

  • Demonstrated excellence in standard laboratory technical skills

  • Detail oriented with the ability to execute complex protocols

  • Proficient at multitasking

  • Excellent organization and documentation skills
About Our Organization

As pioneers in sequencing with a rich heritage in diagnostics, Roche's Sequencing Unit is committed to a future that fosters innovation to provide solutions that enable scientific discovery and deliver clinical value – We are Changing Science and Changing Lives.

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