Sr. Scientist, Oncology Assay Innovation

Roche Sequencing
Job Location
Pleasanton, CA
Job Description


  • Designs, plans and executes assigned research and/or development-related experiments/projects utilizing established and innovative procedures.  

  • Makes recommendations, and when appropriate, acts independently to resolve scientific problems encountered during experimental procedures to improve productivity of results.  

  • Ensures activities are consistent with project critical path, and responds appropriately to changing priorities.   

  • Accurately and consistently records experimental methods, materials and results in electronic laboratory notebooks.

  • Analyzes data, evaluates results, forms conclusions and implements/documents process improvements.  Integrates previous and current results to determine next experimental steps and the impact of long-range project goals.

  • Participates in critical decision making that will impact project team(s) and/or broader organization. Inappropriate decisions may cause a delay in operations, a financial expense and/or customer dissatisfactions.

  • Troubleshoots and resolves difficult problems in creative ways by taking a new perspective on existing solutions, exploring and implementing new concepts and methodologies.

  • Presents findings at group or departmental meetings.  

  • Applies advanced technical writing skills to produce reports and documents.  

  • May assist in preparing summaries, memos, internal reports, presentations, manuscripts, etc.

  • Serves as a resource to other departments (e.g., Manufacturing/Operations, Quality, Marketing, Regulatory Affairs, Clinical Studies, and International Technical Services), provides timely response and follow-ups.  

  • Participates in the expeditious transfer of products and technologies by providing scientific knowledge and assistance



  • Must have PhD in Biological/Life Sciences, Chemistry, Biochemistry or related field.

  • Must have at least 5 years of experience (academic or industry) including direct experience with NGS library preparation, targeted enrichment, and assay development.



  • Direct experience with nucleic acid (NA) based technologies, including NA extractions from tissue and blood samples, designing and optimizing primers and probes for multiplex PCR, real-time PCR and RT-PCR assays.  

  • Experience relevant to the assay development process.

  • Direct experience with NGS library prep, target enrichment, and assay development.

  • NGS data analysis experience is a plus.  

  • Basic understanding and knowledge of cancer biology is a plus.

  • Desire and drive to work on a fast-paced and highly collaborative team

  • Demonstrated excellence in standard laboratory technical skills

  • Detail oriented with the ability to execute complex protocols

  • Proficient at multitasking

  • Excellent organization and documentation skills
About Our Organization

As pioneers in sequencing with a rich heritage in diagnostics, Roche's Sequencing Unit is committed to a future that fosters innovation to provide solutions that enable scientific discovery and deliver clinical value – We are Changing Science and Changing Lives.

At Nature, Johns Hopkins' Gundula Bosch describes her graduate program that aims to get doctoral students thinking about the big picture.

Patricia Fara writes about childcare funding, and women in science and science history at NPR.

National Institute of Environmental Health Sciences researchers have visualized the career paths of former postdocs.

A new survey from the Pew Research Center finds that half of women working in STEM have experienced gender discrimination at work.