Sr. Scientist, IVD Assay Development

Roche Sequencing
Job Location
Pleasanton, CA
Job Description
  • The Senior Scientist in the Roche Sequencing Unit will be part of the assay development team focusing on the development of IVD assays and applications for use on cutting edge next-generation sequencing systems. More specifically, the individual will implement research strategies for the development of genetic testing assays.
  • Experience with IVD assays and applications is essential (ideally 5 years).
  • Experience with NGS, restriction/ digestion enzymes, RNA techniques, nucleic acid/ protein methods, and PCR assay design is highly desirable.
  • Computational experience analyzing large sequence datasets and/or experience with genomic analysis software is a plus.
  • Analyzes experimental data using various data analysis software and/or applying quantitative methods.  Forms conclusions, and provides/documents process improvements. 
  • Uses technical writing skills to produce reports and documents.  May present findings at internal meeting.
  • Works under general supervision, to conduct and monitor laboratory experiments utilizing established and published procedures, and technical and theoretical understanding. 
  • Makes recommendations to resolve problems encountered during experimental procedures.  Assumes responsibility for the accuracy, quality, and timeliness of experimental results.  Summarizes experimental results, and reviews conclusions with supervisor/project leader. Communicates results of experiments in the form of reports and presentations.  Keeps supervisor/project leader informed of project status, particularly of significant findings and results in critical problem areas.  Performs work according to established internal safety guidelines and procedures, and as specified by appropriate external regulatory agencies (e.g., OSHA).
  • Assumes accountability for own electronic notebook documentation, ensuring experimental methods and results are recorded timely, accurately and consistently, and according to established formats. 
  • Participates in routine lab maintenance, lab safety, ISO, and QSR implementation.
  • May troubleshoot issues related to instrumentation.
  • Receives general instructions; plans and executes own work.  
  • Keeps informed of trends and developments in area of scientific responsibility.
  • May establish and work with individuals or teams outside of immediate functional area or RMD. 
  • Knows and effectively uses the broad concepts of a particular filed or specialization to resolve problems of limited scope and complexity.  
  • Analyzes alternative approaches to solve problems or develop new perspectives on existing solutions. 

May act as a lead for assigned projects or team. 


Minimum (required): Bachelor’s degree in Biological/Life Sciences, Chemistry, Biochemistry or related field, or equivalent combination of education and work experience.

Preferred: Master’s degree

Minimum (required): Typically 5 to 7  years of relevant industry experience.

Preferred: 6 to 8 years of relevant industry experience.


About Our Organization

As pioneers in sequencing with a rich heritage in diagnostics, Roche's Sequencing Unit is committed to a future that fosters innovation to provide solutions that enable scientific discovery and deliver clinical value – We are Changing Science and Changing Lives

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