Sr. Scientist - Diagnostics Development

Job Location
San Diego, CA
competitive salary, bonus, stock options

full benefits package effective start date

Job Description

As a member of the R&D Diagnostics Development team, the Sr. Scientist will plan and execute assay develop projects, utilizing targeted enrichment, amplification approaches and next-generation sequencing. The ideal candidate will have extensive knowledge of biochemistry and molecular biology and a proven track record in development of novel nucleic acid detection assays. The ideal candidate will have demonstrated a profound scientific background and published successes in NGS based assay development including statistical data analysis and such as JMP or R. Previous experience managing Sr. Research Associates in preferred. Previous experience with technical project leadership is desired. This is an exciting opportunity to be part of a dynamic R&D team and have the opportunity to work on cutting edge technology. Responsibilities: • Creation and optimization of novel diagnostic assays • Next Generation Sequencing assay development • Next Generation Sequencing assay, data analysis • Develop and leverage targeted assay enrichment approaches including multiplex PCR, bead based enrichment • Design and execute appropriate model systems for proof-of-concept studies • Design and execute appropriate analytical verification studies • Perform data analysis with graphical representations of findings using appropriate software (R, Excel, JMP) • Document all work in the form of laboratory notebook, study reports, summary reports and presentations • Present data clearly and concisely at departmental meetings and project meetings • Participate and present findings at conferences • Publish scientifically relevant data in peer reviewed journals • Participate in the development of patent applications, if applicable • Independently and/or collaboratively conceive initiate and apply for the acceptance of new projects


Requirements: • PhD in Molecular Biology / Biochemistry or a related field • 6 - 8 years’ industrial experience in an applied research and/or development environment • Experience with creation and optimization of novel next generation based assays • Experience with targeted NGS enrichment technologies • Experience with multiplex assay design • Expertise in genomics or genetic assays • Strong background in experimental design, using DOE for assay optimization. • Strong background in data analysis using statistical software packages including R or JMP • Hands-on experience with qPCR • Hands-on experience with next-generation sequencing • Experience managing Sr. Research Associates • Experience with prenatal, oncology and/or infectious disease assay development is as plus. To apply, please visit: EEO/AA M/F/V/D

How to Apply
About Our Organization

Sequenom Laboratories, a wholly-owned subsidiary of Sequenom, Inc., is a CAP accredited and CLIA-certified molecular diagnostics laboratory, dedicated to the development and commercialization of laboratory-developed tests (LDTs) for prenatal and ophthalmic diseases and conditions. As a life sciences company, Sequenom (NASDAQ: SQNM) has a guiding vision: To improve healthcare by providing revolutionary genomic and genetic analysis solutions for the clinical research and molecular diagnostic markets. What makes this vision a reality? Our deep commitment to "Quality of Science." For us, only the highest quality is acceptable. Sequenom team members thrive in a "science first" environment where ideas and innovation are part of daily life. This is your opportunity to work on cutting-edge science that is revolutionizing patient care. Our innovation-driven culture means life at Sequenom is fast-paced, dynamic, and fun with rewarding benefits and performance rewards. With a clear vision for the future, all employees have the opportunity to make a difference and are encouraged to share new ideas. We foster a collaborative work environment and encourage curiosity at all levels. Our corporate headquarters is located in the heart of San Diego’s life sciences community, less than a mile from the beach.

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