Sr. Research Associate

Mount Sinai Genetic Testing Laboratory - Connecticut
Job Location
Job Description

Primary Duties and Responsibilities:

• Generate large, multiplexed pools of amplicons and construct libraries from isolated  

  gDNA using automated methods in a diagnostic setting.  

• Track and enter sample information using a Laboratory Information Management

  System (LIMS).

• Amplify libraries using automated methods and perform Next Generation Sequencing


• Using established Standard Operating Procedures (SOPs), maintain and oversee

  library handling, tracking, and storage.  

• Use a keen attention to detail to maintain sample integrity and identification throughout

  entire workflow.

• Strict adherence to local, regulatory, and quality management guidelines to ensure full



• Bachelor’s degree in life science-related discipline.  

• Exposure to potentially infectious clinical specimens in a biological safety level  

  laboratory environment.

• 5+ years experience with standard molecular techniques:

  • PCR, qPCR, electrophoretic methods, DNA quantification, purification, and pooling methods, enzymatic manipulations, and primer design. 

  • NGS library preparation experience is a huge plus.

  • Experience with operating and programming liquid handling systems is preferred.

• 2+ years experience operating NGS systems.  Experience with multiple platforms is a


• Experience developing and/or performing high complexity lab-developed tests

  (LDTs) is a plus.

• Experience in a CLIA/CAP-accredited facility is preferred. 


Physical Requirements:

• Use personal protective equipment.

• Stand or sit for extended periods of time, potentially performing repetitive motion.

• Work with potentially toxic, flammable, and corrosive chemicals, in addition to biologic   


• Able to lift 30lbs.

• May be asked to work weekend, irregular, or overtime hours.

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