Provides bioinformatics leadership, analysis and software development support to enable interpretation of genomic data. Works with the Director of Bioinformatics to design and develop analytical solutions that integrate with and augment existing informatics capability within the genome center and the hospital. Works directly with medical and scientific staff to define computational strategies and assist with experimental design and hypothesis generation. Performs in-depth analysis for research projects and assist in the definition, validation and implementation of clinical applications. Assists with personnel management as needed with a focus on leading efforts within a defined project or primary functional area of expertise.