Sr. Bioinformatics Scientist

Roche Kapa Biosystems
Job Location
Wilmington, MA
Job Description

Roche Kapa Biosystems is looking for an outstanding Sr. Bioinformatics Scientist to join the team. Kapa Biosystems, located in Wilmington, MA, is a leading developer, manufacturer and supplier of life science reagents for DNA and RNA amplification, sequencing, molecular diagnostic and applied testing applications.

As a Sr. Bioinformatics Scientist you will be leading bioinformatics activities for internal applications projects, including consulting during experimental design and working closely with experimental researchers to generate/provide analysis reports, project reports and perform requested custom analyses to ensure that project goals are met within specified timelines.

 In this position you will:

  • Serve as a functional expert to the technical support team, assisting in investigating and troubleshooting key account customer issues, ensuring that data is received and processed in a systematic, replicable, traceable and timely manner, as well as communicating results to the customer.

  • Ensure that processed data is made available to internal and external customers in a clear, concise and informative format.

  • Expand existing and developing new in-house bioinformatics capacity, including the creation, maintenance and utilization of data analysis and visualization pipelines.

  • Expand/manage compute resource requirements; coordinate the procurement and installation of new compute resources as needed.

  • Stay current on emerging NGS platforms and applications, along with associated data types and analysis paradigms.


To be successful in this role you will have a PhD or MS in a relevant subject (Bioinformatics, Computer Science, Computational Biology, or a closely related subject) with three or eight years’ experience, respectively.

Additionally you will have:

  • Broad knowledge of bioinformatics methods appropriate for Next Generation Sequencing  (NGS) applications, such as targeted sequencing, whole exome sequencing (WES), RNA-Seq, ChIP-Seq, Methyl-Seq/Bis-Seq, whole genome sequencing (WGS)

  • Hands-on experience designing, developing, and documenting bioinformatics pipeline solutions for NGS applications

  • Experience with genome alignment, mapping, variant calling, differential expression, and annotation

  • Demonstrated experience in one or more scripting/programming languages, such as Perl/Python, Bash, C/C++

  • An understanding of next generation sequence sequencing methods, quality scores, and their interpretation

  • Experience with open source bioinformatics tools (e.g., BWA, Picard, SAMtools, GATK, Bowtie)

  • Basic knowledge of methods in statistics; working knowledge of R

  • Experience with Linux system setup and management and/or high performance computing environment setup and management

  • Knowledge of molecular genetics and genomics


How to Apply

To apply, please visit  Job ID#3397102059.

About Our Organization

Roche Kapa Biosystems is a life science reagents supplier that employs proprietary, directed evolution technologies to optimize enzymes for PCR, real-time PCR, next-generation sequencing and molecular diagnostic applications. Kapa Biosystems offers a portfolio of best-in-class products containing novel enzymes that confer significant performance advantages when compared to traditional wild-type enzymes.  The company is based in Wilmington, Massachusetts with a research, development and manufacturing facility in Cape Town, South Africa.

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