Senior Systems Engineer

Pacific Biosciences
Job Location
Menlo Park, CA
Job Description

The ideal candidate will have a BS/MS in optics, electrical, mechanical, or systems engineering with several years of experience using, building & integrating complex instrumentation in a bio-tech environment. The candidate must have excellent analytical and problem solving skills, be a strong team player, able to take initiative, detail oriented, and be able to work effectively as part of a team. She or he will be an excellent communicator working in a fast-paced interdisciplinary environment interacting with scientists, software, and design engineers from a variety of backgrounds.

As part of the Systems Engineering group, the candidate will be responsible for functional test and evaluation of the various modules and device prototypes, and help enable the best design trade-offs across the various disciplines (software, instrumentation & optics, chemistry and semiconductor). The candidate will be also be responsible for defining metrics, developing protocols & tools, reviewing test plans with the design engineers, understanding system performance and troubleshooting performance-related issues.

Hands on with strong optical knowledge (free-space and guide optics), she or he will align & troubleshoot modules & systems and work closely with design teams to understand and resolve product performance issues. He or she will also work on special projects developing test platforms or tooling involving lasers, sensors, optics & opto-mechanics, & robotics.


- BS/MS in Optical, Mechanical, Electrical, or Systems engineering or physics related field with 3+ years of experience
- Strong hands-on experience in working with guided and free space optics, lasers & metrology equipment
- Knowledge in opto-mechanics, optical mounts, electro-mechanical actuators, jigs and fixtures of various sorts
- Familiarity with Matlab, JMP, & a scripting language such as Python is a must.
- Excellent trouble-shooting and data analysis skills.
- Experience with automation, integration and test of instruments used in biotechnology industry, including reagents, biochemistry, and liquid-handling devices (manual pipetting and automated fluidics) is a plus
- Experience with state-of-the art sensor technology (CCD or CMOS) and characterization a plus
- Experience in all phases of the product development cycle from basic research, development, manufacturing and field support.
- Excellent interpersonal, communication and presentation skills
- Product development and / or industry experience in a multi-disciplinary biotech environment is a plus.

About Our Organization

Pacific Biosciences’ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research. The company has developed a novel approach to studying the synthesis and regulation of DNA, RNA and protein. Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, Pacific Biosciences has created a powerful technology platform called single molecule, real-time, or SMRT™, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform the understanding of biological systems by providing a window into these systems that has not previously been open for scientific study.

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