Stanford Clinical Genomics Service (SCGS) is a joint effort between Stanford Health Care (Stanford Hospital & Lucile Packard Children’s Hospital) and Stanford School of Medicine to provide best-in-class clinical genomics sequencing service for patients with unexplained heritable diseases and inherited cancer predisposition. As a member of SCGS, you will be joining a large team of Clinical Lab Scientists, BioInformaticians, Clinical Data Scientists, Curators, Genetic Counselors and Physicians working together to help provide genomics driven Precision/Personalized Medicine to patients. SCGS provides a unique opportunity to do both Clinical Genomics and research in Translational Genomics through collaborations with research labs within Stanford School of Medicine. SCGS is fully funded and is not dependent on Grants for its operations. We offer competitive salaries (even by Bay Area industry standards), generous benefits and a collaborative work culture with mutual respect.
Sr. Staff Scientist – Algorithms will be responsible for leading the algorithm development efforts within SCGS. This position will be responsible for evaluating current algorithms and develop a "best-practice" set of algorithms for use in a clinical diagnostics setting. This position will be responsible for guiding and mentoring other junior members of the algorithm development team. This position will interface with the Curation team to identify gaps in variant detection and annotation and develop novel algorithms and methods to fill those gaps.
Lead the algorithm development group and efforts with the goal of developing NGS algorithms that serve as NGS community standards.
Develop new and/or improve upon existing algorithms for genome assembly, variant detection (SNPs and InDels) and Structural Variant detection (CNVs, Inversions and Translocations) for clinical grade genomic analysis pipeline.
Develop algorithms for novel fusion detection.
Establish new and leverage existing collaborations with research groups within Stanford and other pre-eminent research institutions.
Maintain a high public profile within the Clinical and Translational Genomics community through publications and presentations in high impact journals and conferences.
Help mentor other junior-level bioinformaticians in the group.
Work closely with the data curators and genetic counselors to help improve the overall solve rate of cases.
Perform other related duties as assigned.