Senior Scientist, Surface

Pacific Biosciences
Job Location
1380 Willow Road
Menlo Park, CA 94025
Job Description

Pacific Biosciences seeks a scientist to join a team working on novel surfaces and assays for cutting-edge, single-molecule DNA-sequencing applications. This position provides an exciting opportunity to work with outstanding scientists and engineers in a highly multidisciplinary environment. The successful candidate will have strong hands-on skills in the modification of a variety of solid substrates for biological immobilization, surface-based assay development for biological applications, a thorough understanding of the interactions between biological molecules and surfaces, as well as quantitative analysis of surface physical and functional properties. 
Responsibilities will include:
-    Development of novel DNA immobilization methods;
-    Characterization of functionalized surface and defects;
-    Surface-based bioassay development;
-    Design and execution of experiments using complex prototype instruments;
-    Data analysis with software tools based on MATLAB, R, and jmp;
-    Working with a cross-functional team on transferring surface processes and assays to manufacturing;
-    Generation of design control quality documentation.


-    Ph.D. in chemistry or a related field, and 5+ years of industrial experience;
-    Surface functionalization for biological applications, and surface characterization;
-    DNA and protein chemistry (hands-on experience working with biomolecules);
-    Ability to work in an interdisciplinary environment;
-    Excellent verbal and written communication skills.

About Our Organization

Pacific Biosciences’ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research. The company has developed a novel approach to studying the synthesis and regulation of DNA, RNA and protein. Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, Pacific Biosciences has created a powerful technology platform called single molecule, real-time, or SMRT™, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform the understanding of biological systems by providing a window into these systems that has not previously been open for scientific study. 

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