Senior Scientist, Reagent Process Development

Organization
Pacific Biosciences
Job Location
1380 Willow Road
Menlo Park, CA 94025
Job Description

Pacific Biosciences is seeking a Senior Scientist, Reagent Process Development, to develop commercial reagent products for our SMRTTM Sequencing system. In this position the person will work closely with the research scientists in demonstrating feasibility, generating product specifications, characterizing the product, developing manufacturing and QC processes and transferring these stable processes to Manufacturing.
Technical skills require that this person is capable of developing manufacturing processes and analytical methods associated with reagents used for DNA/RNA sample preparation to polymerase based sequencing. Operation skills require the ability to structure manufacturing processes, such as BOMs, routing, shelf life, and lead times. This person will have experience in utilizing various project management tools, design tools and statistical analysis tools to ensure the delivery of robust, reliable and accurate processes to routine manufacturing.
This person will interface with a broad range of organizational groups and outside vendors, and needs to have good communication skills.

Responsiblities:
•    Delivering well characterized, robust and reliable processes to manufacturing.
•    Lead role in development projects, from conception to completion (transfer to manufacturing).
•    Source and qualify external vendors.
•    Establish relationship between product performance, physical specifications and manufacturing capabilities.
•    Extensive lab work designing and executing experiments, and analyzing resultant data.
•    Identifying opportunities for process improvements.
•    Document newly developed processes and train manufacturing personnel.

Requirements

•    Ph.D. in Molecular Biology, Biochemistry, or related scientific discipline.
•    A minimum of 5-15 years of relevant industry experience in life sciences, medical devices, diagnostics, biotechnology, pharmaceutical or related scientific fields.
•    Has strong experience in developing processes and test methodologies associated with molecular biology based products, preferably in DNA/RNA library construction and sequencing technologies.
•    Experience in commercializing molecular biology reagent kits.
•    Knowledge of analytical tools used for characterization.
•    Experience in a relevant development / manufacturing environment.
•    Broad chemistry knowledge of organic compounds, enzymes and nucleic acids.
•    Excels at troubleshooting and developing corrective solutions and completing projects on schedule.
•    Must be able to design effective experiments followed by thorough data analysis.
•    Appreciation of process quality and specifications as a requirement for manufacturing.
•    Must be hands on, willing to get into the lab to execute to plan.
•    Excellent documentation skills (writing SOPs and Batch Records).
•    Effective verbal and written communication skills.
•    Strong collaborative and team work attributes.
•    Ability to take initiative.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

Students whose classmates are interested in science are more likely to think about a career in science, technology, engineering, and mathematics, a new study says.

CNBC reports that the genetic counseling field is expected to grow as personalized medicine becomes more common.

Gladys Kong writes at Fortune that her STEM background has helped her as a CEO.

Social scientists report that the image of the 'lone scientist' might be deterring US students from STEM careers.