Senior Scientist, Protein Biochemistry

Job Location
Lake County, IL
Job Description

Seeking a highly-motivated and experienced research scientist to join the Protein Sciences group at our corporate headquarters located in the Chicago area. The candidate will be working in a highly dynamic group to provide protein biochemistry support for a newly formed team focused on the therapeutic potential of the ubiquitin proteasome system (UPS). This individual will function as a core-team member of the newly formed inter-disciplinary team, and contribute significant scientific advances to meet project goals. The applicant should be highly skilled in recombinant protein engineering and purification. He/she should have extensive experience working with multi-subunit complexes and working with different expression systems and have a solid understanding of structural biology, protein sciences, biophysics and enzymology. Experience of working with E3 ligases family proteins is highly beneficial. Hands-on experience in molecular biology, protein expression, and other protein characterization techniques will be a strong plus. 
Key Responsibilities: 

• Express and purify proteins to support assay development, HTS screen, biophysical assays and crystallization. 
• Critically QC protein reagents for different applications. 
• Closely work with project biology group to understand project needs and design proper experiments 
• Read literature to provide clone design ideas and other protein biochemistry suggestions 
• Evaluate scientific literature critically and adopt novel technologies to facilitate research 
• Work independently on the design, execution, and interpretation of experimental results


Basic Qualifications: 

• Bachelors, Masters, or PhD in Biochemistry, Biophysics or related field 
• 0+ (Ph.D), 8+ (MS) or 10+ (BS) years of relevant academic and/or pharmaceutical industry 
• Experience with Ubiquitin Proteasome system essential 
• Extensive experiences in the area of making recombinant proteins for assay development, biophysical studies and structural studies. 
• Good problem-solving skills, capable of finding innovative ways to overcome issues (i.e. solubility, purity, heterogeneity, yield) with challenging proteins. 
• Fermentation and molecular biology experience will be a strong plus. 
• Strong communication skills and the ability to contribute in a multidisciplinary environment are essential. 
• Good record keeping and the ability to manage several projects simultaneously in a dynamic environment. 
Preferred Qualifications: 

• 3+ years of academic or industry experience 
Key Leadership Competencies: 

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. 
• Learns fast, grasps the "essence" and can change course quickly where indicated. 
• Raises the bar and is never satisfied with the status quo. 
• Creates a learning environment, open to suggestions and experimentation for improvement. 
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

A research duo finds that science and technology graduate students who turn away from academic careers do so because of changes in their own interests.

Students whose classmates are interested in science are more likely to think about a career in science, technology, engineering, and mathematics, a new study says.

CNBC reports that the genetic counseling field is expected to grow as personalized medicine becomes more common.

Gladys Kong writes at Fortune that her STEM background has helped her as a CEO.