Close Menu

Senior Scientist, Organic Chemistry

Pacific Biosciences
Job Location
1305 O'Brien Drive
Menlo Park, CA 94025
United States

PacBio offers a wide range of programs and services designed to help our employees grow in their career and achieve an appropriate work/life balance. We support the inclusion of all employees and take pride in being an excellent career choice.

Our compensation and benefits packages are designed to motivate and recognize quality work. While specific offerings vary by country, programs may include:

Healthcare and insurance plans

  • Medical, dental, and vision insurance plans
  • Life and accident insurance
  • Travel insurance
  • Disability insurance
  • Healthcare pre-tax spending accounts
  • Health savings account

Family benefits

  • Dependent pre-tax spending accounts
  • New parent leave

Commuting benefits

  • Commuter/parking pre-tax spending accounts
  • Shuttle service to and from local Caltrain stations
  • Bike lockers and shower facilities

Financial planning

  • Restricted stock units
  • 401(k) plan


  • Annual Health Fair
  • Employee assistance programs and work-life assistance
  • Fully equipped on-campus fitness center
  • Certified instructor-led fitness classes
Job Description

Pacific Biosciences is seeking an experienced and highly motivated synthetic organic chemist to further the development and understanding of our single molecule, real-time DNA sequencing technology. The ideal candidate for this role will have experience designing, synthesizing, purifying, and analyzing various fluorescently labeled compounds for bio-assays. Prior experience in the synthesis and modification of fluorescent dyes and conjugation of dyes to biologically active molecules is highly desirable. Additional skills in nucleotide, surface, or polymer chemistry are also valuable. The successful candidate will enjoy working closely with others as a member of an interdisciplinary team.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.



  • Ph.D. in organic chemistry 
  • 2 or more years of postdoctoral or industrial experience, preferably in the life sciences area
  • Strong background in synthetic organic chemistry
  • Experience in fluorescent dye chemistry or nucleotide chemistry
  • Working knowledge of analytical techniques such as LCMS, NMR, absorption and emission spectroscopy
  • Knowledge of photophysics and/or photochemistry would be beneficial
  • Working knowledge of fluorescence and its application would be helpful
  • A basic knowledge of molecular biology and biochemistry is desirable
  • Sharp problem-solving skills
  • Ability to work in an interdisciplinary team of scientists 
  • Attention to detail, careful record-keeping, a high level of organization, and good verbal and written communication skills

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

How to Apply

Please apply at:


About Our Organization

PacBio is the leading provider of high-quality sequencing of genomes, transcriptomes & epigenomes.

Science reports that faculty members are concerned about the risks reopening universities during the coronavirus pandemic pose.

Inside Higher Ed reports faculty members want a say in re-opening discussions.

Inside Higher Ed reports the Centers for Disease Control and Prevention has recommendations for how universities could keep students safe if they return to campus.

At Nature Careers, a postdoc gives advice for graduate students who have to do their PhD defenses remotely.