Senior Scientist – Oncology, Circulating Tumor DNA

Job Location
San Diego, CA
Competitive Base + Bonus + RSU equity


Job Description

Illumina is a dynamic life sciences company developing groundbreaking sequencing and microarray technologies for genome analysis. Our growing Oncology department is striving to develop technologies that will transform basic cancer research and improve diagnostics and prediction of treatment response in cancer by using medical specimens such as archived tissue samples, blood samples and circulating tumor DNA. As a Senior Scientist in Illumina’s Oncology Business Unit, you will work as part of a multi-disciplinary team to help create sequencing based technologies for basic cancer research and clinical oncology applications; Initiates, directs and executes scientific research and development strategies for genetic and epigenetic analysis of circulating tumor DNA. You will be responsible for the development of sample-to-report products for the research and diagnostic markets. Tasks and Responsibilities: • Initiate, direct and execute pre-regulatory scientific research and/or development through managing a small team or individual studies. • Take a leadership role in projects and guide technical areas independently. Make decisions involving designing, performing, troubleshooting, analyzing and presenting experiments • Manage goals within defined target timeframes and make decisions regarding the goals and progress of small project teams. • Write reports and present results and project assessments to Senior Management. • Work closely with scientific, analytical, engineering, and commercial teams to develop, transfer, and sustain new products. • Develop infrastructure processes for product development and manufacturing systems. • Interface with various departments and serve as internal consultant. • Makes significant contributions to scientific literature and conferences. • Solve complex technology and development challenges. • Optimize existing methods, improving processes and scaling up. • Perform data analysis. • Perform other duties as assigned. EOE/Minorities/Females/Vet/Disability


Preferred Educational Background: • PhD or MD in cancer research, molecular biology, genetics, genomics or related field. Preferred Experiential Background: • 5-8 years (post-PhD) experience in the field of technology and/or commercial product development is required with sound foundation in cancer research, cancer diagnosis, genomics and next-gen sequencing. • Proven track record of technology and/or product development in a fast paced biotech environment. • Experience with handling archived tissue samples, blood samples and circulating tumor DNA. Experience with DNA and RNA based genomic assay development with control materials and QC metrics. • Outstanding publishing record, patent history, or other evidence of scientific excellence. • Must be able to design experiments and perform data analysis for others and have demonstrated experience in achieving results with team members in non-biological disciplines. • Ability to translate corporate goals into executable plans understanding technical risks, mitigations and alternatives. • Good data analysis and interpretation skills. • Excellent communication and team management skills. • Highly motivated, detailed individual with the proven ability to think innovatively toward solving problems effectively and efficiently • Experience with development for regulated markets and design controls highly desirable. • Experience with transfer of new products to manufacturing and/or QC desired.

How to Apply

Apply at and search on Req 1498BR.

About Our Organization

About Illumina Illumina ( is a leading developer, manufacturer, and marketer of life science tools and integrated systems for the analysis of genetic variation and function. We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA, and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare.

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