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Senior Scientist - Immuno-Oncology, Bioinformatics Data Analyst

Organization
Sanofi Immuno-Oncology - Precision Oncology
Job Location
270 Albany Street
Cambridge, MA 02139
United States
Job Description

The Oncology Research Therapeutic Area seeks an experienced computational biologist / data scientist to join us in the fight to stop cancer.

In this exciting role the Data Scientist is an integrated part of Discovery teams and will design experiments, manage data, and use advanced statistical, machine learning, as well as computational techniques to discover new targets either to stop the growth of cancer or re-awaken the immune system to eradicate the cancer. Furthermore, the Data Scientist will collaborate with Early Development teams to guide the development of molecules against those targets with data-driven biomarker plans.

Summary of Key Responsibilities:
• Proactively engage with project teams to define crisp scientific questions that can be addressed with an appropriately powered experimental designs
• Supply any computational, statistical, machine learning or modeling capability needed to synthesize from this design actionable recommendations relative to the team’s question
• In collaboration with project teams propose analysis strategies for target discovery, using methods based for instance on differential expression, co-regulation, correlated amplification, recurrent alterations, etc.; in so doing, also help devise statistical metrics for deciding significance, and ranking schemes for integrating data from many sources
• Identify targets and biological contexts (e.g., T or B-cell repertoire, immune phenotypes, copy number, mutational, or expression signatures) in which therapies are likely to be beneficial by mining immune, genetic, genomic or screening data
• Identify from patient and model system databases the epidemiology of these biological contexts and targets
• Develop biomarker plans (e.g., selection, PD, efficacy) in collaboration with project teams
• Manage and develop group of one or more associates and/ or contractors

Requirements

• Ph.D. in a computational, statistical, biophysics, or bioinformatics related fields.

• A minimum of 3+ years project-based work in computational application to biology related fields


About Our Organization

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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