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Senior Scientist - Complement Expert

Organization
Gyroscope Therapeutics
Job Location
London
London
London
United Kingdom
Salary
Very competitive
Benefits

We are a young compnay and are constantoy adding benefits for our employees. So far these are:

Generous Bonus scheme

Pension – 9% employer contribution

Private Medical Health (family)

Life Assurance ( 4 x salary)

Income Protection Insurance

Parental enhanced pay

25 days holiday (plus days between Christmas and New Year – no need to use holiday for this shut down period)

Travel Insurance

Cycle to work scheme

Free parking

GSK offer subsidised gym on site (however, Vitality offer other subsidised gym memberships)

On site coffee shops/restaurant/dry cleaning services

(Piloting a 4 day week in August)

Job Description

The Complement Expert will act as scientific lead for New Target Identification, develop and refine new complement-based assays and will coordinate assay development activities across project boundaries with other functional areas within Research.

 

The expectation is that this individual will represent Research on project teams. The successful candidate will have the ability to complete work in a resourceful, self-sufficient manner and is able to design research projects to achieve desired outcomes.


Key Responsibilities:

 

  • Responsible for scientific insights related to driving new target discovery, understanding of mechanism of action, and rationale for indication expansion
  • Represent Research within multidisciplinary project teams
  • Contributes to technical assessment as part of due diligence activities
  • Participates in the selection of CROs and academic collaborators via technical assessments
  • Collaborates with project team to develop study designs
  • May assist in the preparation of internal documents and Regulatory submissions, including authoring (under supervision)
  • Performs other duties as assigned
Requirements

 

Required attributes:

 

  • Proven track record in identifying and validating targets within Complement biology
  • Possesses a distinguished record enabling the goals of the assigned projects
  • Demonstrates excellence in his/her own discipline and/or area of pursuit
  • Demonstrated strong aptitude to lead a group or team endeavour, and building team unity
  • Demonstrated project management experience
  • Skilled in designing research projects including short and long-term plans
  • Demonstrated ability to compile and analyse study data with limited oversight
  • Excellent verbal presentation and written skills
  • Demonstrated ability to solve complex problems to attain crucial project goals

 Qualifications:

  • Ph.D. or M.Sc or B.Sc and demonstrable work experience
How to Apply
About Our Organization

Gyroscope Therapeutics is a clinical-stage retinal gene therapy company, developing cutting edge medicines to treat eye diseases linked to a part of the immune system called the complement system. The company was founded to capitalize on a convergence of advancements made in the understanding of the complement system’s impact on eye disease, the genetic basis of Age-related Macular Degeneration (AMD) and gene therapy as a mode of treatment delivery.

Recently, Gyroscope Therapeutics merged with Orbit Biomedical to create the first fully integrated retinal gene therapy company with a promising investigational medicine, high quality manufacturing and a surgical platform that can support accurate, safe and consistent delivery to patients with blinding conditions. Gyroscope’s lead investigational medicine, GT005 is being studied in the Phase I/II FOCUS trial in advanced dry AMD. GT005 is a novel retinal gene therapy that delivers a targeted, single dose treatment for the progressive visual impairment caused by dry AMD in patients by locally modulating complement activity.

Gyroscope is building a pipeline of medicines for blinding eye diseases linked to the complement system.   Orbit Biomedical Inc., is a medical device company and subsidiary of Gyroscope, operating at the intersection of gene and cell therapy, engineering technology and surgeon education. Our goal is to revolutionize gene and cell therapy treatment by setting a new standard for precise, targeted surgical delivery. Orbit Biomedical’s technology, the result of many years’ work, is designed to safely and consistently deliver gene and cell therapy medicines, initially for the treatment of retinal disease. Orbit plans to use its proprietary delivery system to support accurate, safe and consistent delivery of Gyroscope gene therapy technologies and to partner with external companies who are developing single-use cell and gene therapies.

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