Date Posted: 8/25/2014
Deadline to Apply: open until filled
The Department of Genome Sciences has an outstanding opportunity for a Research Scientist/Engineer Senior (RSE Sr). The RSE Sr will play a leading role in providing biological and genomic insight required to help steer the computational and informatics efforts of the lab. The person in this role will work to emphasize the efforts of understanding gene regulation, chromatin, regulatory variation, and its relation to human disease. He/she will also support the laboratory applications of high-throughput DNA sequencing methods for a variety of epigenomic assays, including DNase-seq, ChIP-seq for histone modifications and transcription factor binding, methylation analysis, chromatin capture analysis, and newer, cutting-edge methodologies currently under development in the lab.
The main responsibilities for this position are as follows:
• Formulate testable hypotheses relevant to the intellectual mission of the lab.
• Design specific scientific projects and experiments that translate regulatory genomics technologies to disease-focused research paradigms
• Work closely with laboratory experimentalists and informatics staff to plan and execute experiments and analyses
• Coordinate large-scale analysis efforts: formulate plans, set milestones, direct and supervise staff to accomplish specific aims.
• Perform customized analyses to solve specific research questions.
• Develop software and scripts designed to analyze genome-wide epigenetic datasets or facilitate dataset production.
• Maintain domain expertise by reading research papers, attending conferences, and maintaining collaborations with relevant investigators
• Prepare written manuscripts for publication; generate production-quality figures using publishing and mathematical modeling software
• Prepare and deliver oral and poster presentations on research results for conferences
• Assist in the organization and writing of grant proposals and project reports
• Attend Genome Sciences and University meetings, retreats, status updates, orientations and planning days when necessary.
Supervise more junior informatics staff in executing large-scale analysis efforts, when required
This position requires deep domain knowledge and research experience, as well as computational skills. The position requires communication and coordination with all levels of laboratory staff. The position directly impacts the success of the laboratory’s research mission by helping to set research priorities and then formulating plans to test hypotheses and execute experiments and analyses. It requires the ability to manage large-scale projects and supervise staff duties within those projects. The position requires maintaining and fostering relationships with University and non-University parties. The position demands organization, commitment, the ability to work alone and in complex teams, expertise in laboratory protocols, and expertise in DNA sequencing.