Senior Research Associate (Sample Management) - 80405
The Department of Energy (DOE) Joint Genome Institute (JGI) offers a unique opportunity to work with DNA and RNA samples from plants, fungal, microbial, and environment for downstream applications. The role is responsible for receiving, accessioning, evaluating, and preparing aliquots of DNA/RNA samples.
Will evaluate the current and newly developed methods to extract DNA/RNA from various organisms and assess the sample quality and quantity and provide logistic recommendations. Will serve in a technical support role to improve the efficiency and quality of sample management processes. Will closely interact with the Sequencing Technologies group members, as well as other technical and administrative support staff, and serve as the point of contact for sample issues. Will report any technical problems that occurred in the sample management process. May provide technical guidance and training to other team members. May need to lift up to 25lbs. frequently and work in a cold environment with freezers at temperatures of -80C. This position reports to the Sample Management group Lead.
• Perform work assignments related to the sample acquisition process including the evaluation of collaborators’ samples, internal sample QC, and aliquot making and tracking.
• Proficiency with DNA/RNA extraction and quality evaluation methods from various organisms.
• Understand next generation sequencing applications and their associated library protocols.
• Participate in continuous improvement, process optimization, development, and implementation projects for advancement and scale-up of sample management process to support next generation sequencing technologies.
• Conduct validation tests of newly developed processes aimed at improving quality, troubleshooting failures, and reducing cost of sample management processes.
• Maintain a complete set of documentations (gel images, Bioanalyzer traces, etc) for all nucleic acid samples.
• Operate robotic and laboratory equipment used in high-throughput sample processing, and perform quality control and maintenance of equipment and robotics.
• Write standard operating procedures and protocols for new methods and cross-train team members on new procedures.
• Maintain a clean and safe laboratory work area and ensure compliance to safety policies; perform daily maintenance, clean up, and workspace organization within assigned work areas.
• Maintain an accurate and detailed laboratory notebook of daily production operations, observe and document any deviations from established protocols and bring them to supervisor’s attention.
• Participate in cross-team and cross-group collaborative projects in Genome Technology Development.
• May maintain a clean and safe working environment.
• May contribute to data, text in group publications.
• May assist group members in performing new molecular biology experiments and protocols.
• May research articles and literature to explore new techniques or applications.