Senior Research Associate (NanoBiology)

Newcastle University
Job Location
School of Computing Science
Claremont Tower
Newcastle upon Tyne
Tyne & Wear
United Kingdom
£38,896 to £41,255 (with progression to £46,414)
Job Description

Main Duties and Responsibilities

1. To lead the experimental aspects of nanobiology at the ICOS research group ( ) experimental facilities located in the Centre for Bacterial Cell Biology ( ), in particular to conduct world-leading research on DNA, RNA and/or PNA origami and/or molecular or cellular computation.

2. Carrying out wet lab experiments to validate models and hypothesises arising on point one above and explore the intersection between Bio/Nano materials, Synthetic Biology and molecular or cellular computation

3. Work with computational colleagues to design in silico what will be implemented in the laboratory (steps 1 & 2 above) and develop appropriate experimental validation and analysis techniques for the above.

4. Developing novel and adapting existing experimental methods and validating them to overcome issues arising from points 1,2 & 3 above thus ensuring the correct experimental implementation of DNA, RNA and/or PNA origami and/or molecular or cellular computation

5. Developing novel and adapting existing imaging methods (SPM, AFM, TEM, etc) for DNA, RNA and/or PNA origami and/or molecular or cellular computation

6. Participate of the ICOS group research activities and play a role in identifying potential funding sources and prepare and write proposals for follow on funding

7. Supervise and provide expert training to research and technical staff, students (PhD, MSc) as well as external visitors to the ICOS group

8. Ensure that work carried out in the molecular microbiology labs meet the appropriate legal, health and safety standards and initiate and implement Good Laboratory Practice for the experiments run in these facilities related to this project and any other project run by the ICOS group within a Responsible Innovation framework.

9. Play a major part in the dissemination of the research findings, presenting at conferences and contributing substantially to publications.

10.Crucially, to produce high quality publications in internationally leading journals and conferences.


Person Specification Knowledge (inc. qualifications)


1. PhD, or Deng in nanotechnology, synthetic biology, molecular microbiology, molecular or cellular computation, biochemical engineering, bio/nano materials, etc.

2. Substantial and demonstrable laboratory experience and be familiar with molecular and polymers techniques, e.g. DNA, RNA or PNA based nanotechnology, origami and/or DNA or cellular computation, genetic engineering, bacterial cloning, construction of gene fusions, use of bacterial reporters, confocal microscopy and AF microscopy, microfluidics, laser or sonic tweezers, etc.


1.  A demonstrable scientific upward trajectory that would place the candidate in a position to, within 5 years, become an independent investigator. Skills (professional, technical, managerial, practical)


1.  Substantial laboratory experience in Bio/nano materials, molecular microbiology, DNA/RNA/PNA origami, molecular/cellular computation.

2.  Good presentation skills

3.  Ability to work independently and as part of an interdisciplinary team

4.  To attend and present research findings at research group meetings (internal and external) and conferences as appropriate, including international visits

5.  Write reports for the funding bodies when required


1.  Demonstrable ability to manage complex projects and to secure funding

2.  Demonstrable experience of ability to communicate complex concepts to colleagues within the same disciplines, other disciplines and the lay person

Experience and Achievements (paid or unpaid)


1.  Work to deadline

2.  Work both independently and as part of a team

3.  Timely reporting

4.  Assistance with supervision of doctoral and project students

5.  Strong record of high quality international publications

6.  Experience of leading a team

7.  Participation and organisation of project-related field work

8.  Collaboration with other group members and the international community

About Our Organization

We are looking for a highly experienced experimental scientists to join our multidisciplinary team. You will join one of the premier interdisciplinary Biocomputing groups in the world, the Interdisciplinary Computing and Complex Biosystems research group (ICOS - ) and Newcastle’s Centre for Synthetic Biology and the Bioeconomy (CSBB - You will be part of a highly interdisciplinary team of PhD students and postdocs, based in the world-leading Centre for Bacterial Cell Biology (

Duties will include the design and experimental realisation of bio/nano devices based on DNA/RNA/PNA origami for molecular and cellular computation. You will make use of a range of techniques and instruments from various disciplines including nanoscience, synthetic biology, biophysics, engineering, computing science and advanced microscopy to build proofs of concepts and demonstrators for these devices. 

You will help the PI drive the exploration of interfacial grand challenges at the intersection of bio/nano materials, synthetic biology and molecular and cellular computation disciplines. You will play a role in identifying potential funding sources and prepare and write proposals for external funding. You should have a PhD orDEng in nanotechnology, synthetic biology, molecular microbiology, molecular or cellular computation, biochemical engineering, bio/nano materials, etc and have proven ability to work at the interface of multiple disciplines (e.g. Computer 
Science, Biology, Nanotechnology).  Prof. Krasnogor will mentor and coach you during grant writing with a view to enabling long-term sustainability for the post.

This position is available immediately and is fixed term for 24 months. 

The School of Computer Science is committed to promoting equality and diversity, including the Athena SWAN charter for promoting women’s careers in STEMM subjects (science, technology, engineering, mathematics and medicine) in higher education. The School received a Bronze Award in 2015 for their commitment to the representation of women in the workplace and we welcome all candidates to apply for this post. 

Appointment will always be made on merit. 

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