Senior Research Associate

Organization
Mount Sinai Genetic Testing Lab - Connecticut
Job Location
Branford, CT 06405
Job Description

 

Primary Duties and Responsibilities:

• Generate large, multiplexed pools of amplicons and construct libraries from isolated  

  gDNA using automated methods in a diagnostic setting.  

• Track and enter sample information using a Laboratory Information Management

  System (LIMS).

• Amplify libraries using automated methods and perform Next Generation Sequencing

  (NGS). 

• Using established Standard Operating Procedures (SOPs), maintain and oversee

  library handling, tracking, and storage.  

• Use a keen attention to detail to maintain sample integrity and identification throughout

  entire workflow.

• Strict adherence to local, regulatory, and quality management guidelines to ensure full

  compliance.

 

 

Requirements

• Bachelor’s degree in life science-related discipline.  

• Exposure to potentially infectious clinical specimens in a biological safety level  

  laboratory environment.

• 5+ years experience with standard molecular techniques:

  • PCR, qPCR, electrophoretic methods, DNA quantification, purification, and pooling methods, enzymatic manipulations, and primer design. 

  • NGS library preparation experience is a huge plus.

  • Experience with operating and programming liquid handling systems is preferred.

• 2+ years experience operating NGS systems.  Experience with multiple platforms is a

  plus.   

• Experience developing and/or performing high complexity lab-developed tests

  (LDTs) is a plus.

• Experience in a CLIA/CAP-accredited facility is preferred.   

 

Physical Requirements:

• Use personal protective equipment.

• Stand or sit for extended periods of time, potentially performing repetitive motion.

• Work with potentially toxic, flammable, and corrosive chemicals, in addition to biologic   

  agents.

• Able to lift 30lbs.

• May be asked to work weekend, irregular, or overtime hours.

How to Apply

Send your resume to [email protected] with the job title you are applying to in the subject line.

About Our Organization

An extension of the Department of Genetics and Genomic Sciences and the Institute of Multiscale Biology in the Icahn School of Medicine at Mount Sinai, our state of the art next generation sequencing facility utilizes a variety of cutting edge, high throughput technologies. Our laboratory will generate huge amounts of sequencing data whose interpretation has the potential to change the face of how medicine is practiced. We will participate in large sequencing projects and analyze large numbers of individuals to gain a better understanding of the biology of cancer and inherited diseases. One of our initial focal points will be The Resilience Project where tens of thousands of DNA samples from healthy adults will be sequenced and analyzed for the presence of rare genetic variants that were expected to cause severe illness in these individuals during childhood.

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