Senior Engineer, Manufacturing

Organization
Pacific Biosciences
Job Location
1380 Willow Road
Menlo Park, CA 94025
Job Description

Pacific Biosciences is looking for a Senior Engineer, Manufacturing to lead the specification, selection, installation, and validation of production equipment for the Reagent Manufacturing Group.   This position requires interfacing with external vendors and internal technical groups, in addition to completing hands on work in a fast paced manufacturing environment. 

 Responsibilities:         
•    Lead development of new equipment for fill and labeling/packaging automation of DNAse/RNAse-free  liquid formulations in plastic vials and plates
•    Lead development of secondary and tertiary packaging systems for  new reagent kits and components
•    Support design and sourcing of equipment to scale up large volume mixing
•    Complete vendor selection, installation, and validation of new equipment
•    Design manufacturing workflows in conjunction with manufacturing managers and external vendors
•    Generate documentation for troubleshooting and maintenance of new equipment
•    Establish preventative maintenance program, schedules, and process monitoring program
•    Maintain production equipment and troubleshoot equipment problems to meet production goals
•    Plan, deploy and maintain MES (Manufactuting Execution System) automations

Requirements

 The Ideal Candidate:
•    Minimum BS  in Engineering or Life Sciences with 5-15 years in biotechnology or pharmaceutical industry
•    Ability to lead projects with external vendors/internal technical experts and at the same time complete hands on work
•    Automation experience in liquid tube vial filling, labelling,  and plate filling for molecular biology products 
•    Experience with handling DNAse/RNAse free liquids containing proteins and/or fluorescent dyes
•    Experience supporting PLC and PC based machine control
•    Experience with NFC tags
•    Experience in ISO 13485 clean room manufacturing environment 
•    Skilled in the use of Statistical Process Controls for Manufacturing
•    Experience with Batch Record automation (MES / electronic work instructions and data collection) for process manufacturing and batch production environment 
•    Effective communication and writing skills for documenting manufacturing work instructions or processes
•    Attention to details and excellent problem solving skills
•    Ability to multitask and  be organized, yet flexible in a fast-pasted, high-intensity work environment  

About Our Organization

Pacific Biosciences’ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research. The company has developed a novel approach to studying the synthesis and regulation of DNA, RNA and protein. Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, Pacific Biosciences has created a powerful technology platform called single molecule, real-time, or SMRT™, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform the understanding of biological systems by providing a window into these systems that has not previously been open for scientific study. 

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