This position at the New York Genome Center is within the computational biology group and will report to the Assistant Director. As a Senior Bioinformatics Scientist, you will be responsible for applying and developing cutting edge analytic methods to large scale cancer exome and whole genome sequencing data generated at NYGC and elsewhere. You will work with collaborators throughout the city and other members of the NYGC computational biology team to provide novel insights into cancer mechanism and treatment, develop and maintain state of the art analysis tools, and analyze cutting edge data from new genomics technologies. Projects can range from large and diverse cohorts of tumor samples (such as generated in the NYGC Polyethnic-1000 project), longitudinal sampling of tumors, liquid biopsy, single-cell genomics (RNA, DNA or multi-modal), etc. You should have significant experience in cancer genomics, including familiarity with commonly used algorithms for alignment, variant calling, and structural variant calling and computational methods for inferring significantly associated somatic variation from cohorts of patients. Publication of developed methods and scientific findings is encouraged. The Senior Bioinformatics Scientist is expected to contribute as an individual but may also be asked to manage a small group working on cancer genomics.
Job duties will include, but may not be limited to:
- Develop and implement innovative computational approaches for the analysis of large datasets generated by NGS technologies;
- Contribute to management of next generation sequencing (NGS) data analysis pipelines;
- Analyze sequencing data using the established pipeline(s);
- Collaborate and consult with external and internal researchers on the analyses of NGS data;
- Interpret and present the results of the computational and statistical analyses to collaborators and coworkers;
- Assist collaborators with data access, analysis, and interpretation;
- Supervise and guide bioinformatics analysts/programmers;
- Contribute to strategic decisions about the cancer genomics efforts at NYGC;
- Participate in grant application writing;
- Publish results in scientific journals and give presentations at conferences; and,
- Participate in community outreach.
- Stay current on innovations in DNA sequencing analysis;