Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.
The Tissue Injury and Fibrosis Research group is seeking independent and motivated scientists to join a newly established research team focused on understanding the molecular basis of fibrotic disease and developing novel therapeutics to treat these diseases. The successful candidate will be responsible for developing in vivo animal of models fibrosis and acute tissue injury and running in vivo pharmacology studies to support target validation and mechanism of action exploration. The candidate may also conduct ex vivo and in vitro studies to support characterization of in vivo responses.
Responsibilities will also include, but are not limited to, the following:
• Develop and run in vivo pharmacology models of fibrosis across multiple organ systems.
• Independently review the relevant literature to understand and propose the best methods that can be applied to the needs of the group.
• Provide strategic input and propose new initiatives for methods to validate novel targets and test therapeutics.
• Hands-on experience and excellent teamwork skills in liaising with other departments.
• Keep abreast of, and use, state-of-the-art technologies in target validation.
• Prepare, review and deliver scientific presentations for internal/external use.
Experience in running fibrosis models of lung, surgical recovery models in rodents and conducting and analyzing PK/PD experiments is an asset. This will include excellent hands on capabilities in working with rodents, model troubleshooting skills and in depth knowledge of cell culture, ELISA, protein signaling, qPCR technology platforms, FACS analysis and assay automation techniques. The candidate must demonstrate a thorough knowledge of experimental design, underlying scientific principles, and the ability to independently assess results. Needs to have a demonstrated track record of leading support activities for multiple research projects, scientific and technical advancement, and co-authorship of peer-reviewed publications. The position requires excellent communication skills and ability to present data, and the ability and willingness to work effectively in a highly collaborative research environment.
Bachelors degree with at least 8 years or of academic and/or industry experience
Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.
Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.
Req ID: 15002190
Primary Location: United States-Massachusetts-Bedford
Job: Research and Development
Organization: Celgene Avilomics Research
Employee Status: Individual Contributor
Job Type: Full-time
Job Level: Day Job
Job Posting: 2015-12-21 00:00:00.0
Biology, Biotech, Cell Biology, Engineering, Healthcare, Medical, Medical Lab, R&D, Research, Research Scientist, Science, Scientific, Scientist, Senior Scientist