Senior Applications Scientist

10X Genomics
Job Location
San Francisco Bay Area, CA
Job Description

10X Genomics is looking for an outstanding scientist to join its Applications Development group. The scientist must have a passion for innovating new applications that use Next Generation Sequencing technologies to drive discovery and improve human health. The scientist must be able to learn quickly, creatively solve problems, and communicate effectively. The ideal candidate will have a PhD or equivalent depth of knowledge and experience in molecular biology, cancer biology, or genetics, especially as applied to NGS applications.

 Key Responsibilities

  • Work with early access customers to test new products and applications
  • Identify key opinion leaders and opportunities for collaboration for application development
  • Develop and run internal product validation efforts
  • Use 10X Genomics’ platform to develop novel NGS applications
  • Produce proof-of-concept data sets to demonstrate the unique power of the 10X Genomics platform internally and externally
  • Write applications notes for users of the 10X Genomics platform

Required Skills and Background

  • PhD or equivalent in molecular biology, cancer biology, genetics, or a related field
  • Deep understanding of the NGS applications space (e.g., sequencing applied to disease diagnostics, RNA, cancer, immune repertoire, single cells, de novo assembly)
  • Experience with existing NGS platforms (e.g., Illumina, Ion Torrent, PacBio, etc.)
  • Demonstrated ability to trouble-shoot complex problems and to work effectively in a multi-disciplinary team
  • An eagerness to dramatically improve NGS tools
  • Strong organizational skills
  • Strong written and oral communication skills demonstrated with peer-reviewed publications and conference presentations
  • Demonstrated ability to maintain relationships with customers or external collaborators


Desired Skills and Background

  • Experience analyzing large sequencing data sets
  • Experience with NGS-related products such as Agilent SureSelect target capture, Ion AmpliSeq, Fluidigm single cell sequencing, etc.
  • Experience with NGS assembly, alignment, and/or variant calling pipelines
  • Experience using reference genome materials/data
  • Deep knowledge of RNA or cellular biology in cancer or immunology contexts
  • Knowledge of study design principles for population genetics or genome-wide association studies
How to Apply
About Our Organization

10x Genomics meets the critical need for long range, structural and cellular information, with an innovative system that transforms short-read sequencing technologies. Our ChromiumTM System supports comprehensive genomics and high-throughput single cell transcriptomics. It enables researchers to discover previously inaccessible genomic information at unprecedented scale, including phased structural variants, phased single nucleotide variants, and dynamic gene expression of individual cells—while leveraging their existing sequencing systems and workflows.

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