Screening Scientist | GenomeWeb

Screening Scientist

Organization
Avacta Life Sciences Ltd
Job Location
Wetherby
United Kingdom
Job Description

General Purpose and Scope

Avacta Group plc is a healthcare technology and consumables company providing proprietary analytical and diagnostics solutions to the life science sectors.

 

We are looking for an enthusiastic and highly skilled scientist to join our team in Avacta Life Sciences developing Affimers, a proprietary non-antibody derived affinity scaffold. Affimers are an engineered alternative to antibodies that have been designed to address issues with specificity, batch to batch variability, current antibody assay limitations, the length of time taken to generate new binders and limitations on potential targets imposed by the use of animals in generating antibodies.

 

Building on our existing Affimer production processes, you will be expected to contribute to process validation and improvement and will work within our Screening Team discovering Affimers to protein targets covering basic research areas and diagnostics. This will involve the use of several display technologies and automated platforms to identify lead Affimers to targets that can then be passed to the Validation Team. You will also be part of the larger Avacta Life Sciences team, and report to the Senior Scientist running the Screening Team.

 

To be eligible for this post, you will have an undergraduate qualification in Molecular Biology or

Biochemistry (or similar biological science) and either a postgraduate qualification or at least 2 years industrial experience. Experience of molecular biology and protein expression in prokaryotes as well as experience of performing immunoassays such as ELISA, Western Blot, Flow Cytometry and/or Immunocytochemistry is essential. Experience of phage display (or similar library screening methodology such as ribosome display or mRNA display) or the use of automation platforms would be advantageous.

 

Successful candidates should have a bold and innovative nature, be able to demonstrate excellent communication, organisational and problem solving skills and have a desire to be fully involved in driving the growth of the business.

 

Main Duties and Responsibilities

  • Use and implement screening methods to discover specific Affimers to a range of targets.

  • Maintain good laboratory records.

  • Communicate experimental detail both verbally and in technical reports.

  • Participate in general process optimisation.

  • Participate in the preparation of technical reports, summaries, protocols, and quantitative analysis.

  • Perform support duties that involve lab maintenance.

  • Comply with, and support the generation of, all safety and quality regulations.

 

 This job description is not exhaustive and you may be required to undertake other duties that are in line with the above responsibilities.

 

 Education/Experience/Skills

Essential:

  • Undergraduate qualification in a Biological Science with either a postgraduate qualification or

at least 2 years industrial laboratory experience.

  • Experience in Molecular Biology, specifically cloning and bacterial protein expression.

  • Experience in one, preferably several, immunoassay techniques (ELISA, WB, ICC/IHC, and FC).

  • The ability to work efficiently and as part of a multidisciplinary team.

  • The ability to work with a high degree of autonomy, professionalism, care, accuracy and

reliability.

  • Excellent organisational skills.

  • Excellent verbal and written communication skills.

  • A bold and innovative nature and a desire to be fully involved in driving the growth of the

business.

  

Benefits

  • Pension Scheme: up to 5% matching contributions

  • EyeCare Scheme

  • Childcare Voucher Scheme

  • Performance Related Share Option Scheme

  • 25 days holiday in addition to bank holidays

     

     Closing date: 14th August 2015

How to Apply

To apply for this position please forward your CV with a covering letter to HR@avacta.com

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