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Scientist/Staff Scientist, Human Disease Modeling

New York Stem Cell Foundation
Job Location
619 West 54th Street
New York, NY 10019
United States
Job Description

The New York Stem Cell Foundation (NYSCF) Research Institute is a rapidly growing and highly successful nonprofit whose mission is to accelerate cures through stem cell research. NYSCF is seeking an Scientist/Staff Scientist to join the stem cell differentiation and functional genomics team within the NYSCF Global Stem Cell Array®. This position reports directly to a Principal Scientist and works closely with members of the wider team including stem cell biologists, automation engineers, software developers, project management, and operations. We are seeking a highly self-motivated applicant with a strong interest in developing functional models of human disease through the use of human pluripotent stem cells. The person will have a strong background in hiPSCs/hESCs, ideally with experience in directed differentiations. This is a full-time position based on a 35-hour workweek, however, some weekend work may be required. Level will be commensurate with experience.What you'll do:

    • Scrutinize, develop, optimize and deploy disease models in a project driven manner through the use of human pluripotent stem cells
    • Functionalize genomic leads by developing and executing morphological, transcriptomic and functional assays to characterize phenotypes
    • Work collaboratively with NYSCF biologists, automation engineers and project management
    • Manage and mentor junior motivated scientists
    • Execute, troubleshoot and communicate tasks independently and effectively
    • Maintain extremely organized and accurate records using an ELN/LIMS
    • Provide regular feedback at inter-team meetings
    • Provide routine scientific reports to project management and outside collaborative parties

What we're looking for:

    • MS with 5+ years of experience or recent PhD (0-2 years post graduation) focused in the stem cell biology field, hiPSC/hESCs cell culture essential
    • Experience with directed differentiation is highly desired
    • Experience with assay development and execution, screening, imaging techniques, gene modification technologies are a plus
    • Demonstrated ability to work both independently and within a multidisciplinary team
    • Excellent written, verbal and interpersonal communication skills
    • A high proficiency in both Mac and/or PC computer environments
    • Experience with Spotfire/GraphPad is a plus
    • Organized and able to prioritize and execute tasks
    • Able to analyze and interpret data and report findings succinctly
    • Adaptability to work in a fast-paced and changing environment requiring occasional weekend work
    • Experience with differentiation toward liver specific lineages, including but not limited to liver organoids, hepatocytes, stellate cells and liver-sinusoidalendothelial cells is a plus
    • Level will be commensurate with experience

NYSCF is an equal opportunity employer and we value diversity at our company. It ensures equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, veteran status, or any other characteristic protected by law.

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