Scientist (Protein Purification)

Lucigen Corporation
Job Location
Middleton, WI
Commensurate upon experience.

Lucigen offers competitive salaries and benefits. For more information, see

Job Description

Lucigen seeks an adaptable and action-oriented scientist to join its growing team. This position is responsible for the production and development of proteins and molecular biology reagents, with a focus on molecular biology and next generation sequencing (NGS) applications. This position:

  • Purifies recombinant proteins from different expression systems in a manner consistent with Lucigen’s ISO 13485 quality systems; independently performs assigned duties in this area
  • Prepares and operates chromatography systems, dialysis/TFF operations, and buffer preparation
  • Performs quality control testing on enzyme activity and functional tests as well as standard protein characterization assays
  • Optimizes existing purification processes to improve product yield and quality
  • Assists in development of protein production protocols geared towards robust and cost-effective supply of molecular biology/NGS proteins
  • Identifies process improvement opportunities based on first-hand observation and data review
  • Processes, records, and analyzes data following approved protocols and using good documentation practices
  • Develops and conducts studies and follows protocols supporting process improvements, investigations, and corrective/preventative actions
  • Maintains cleanliness and orderliness of operational area
  • Effectively communicates results to the Lucigen team
  • Plans, schedules, and manages assigned functions and product families to provide product to meet the production plan and customer requirements
  • Delivers high-quality documentation consistent with Lucigen’s quality systems

This position requires a Master’s degree in relevant life sciences field (molecular biology, microbiology, biochemistry, etc.) with 0-3+ years’ experience in protein production and purification in an industrial setting; or Bachelor’s degree in relevant life sciences field with 3+ years’ industry experience; or Associate’s degree in relevant life sciences field with 3-5 years’ industry experience. Additional requirements include:

  • Experience in standard biological and analytical techniques, including PCR, SDS-PAGE, and western blotting
  • Demonstrated hands-on experience in protein purification using both manual and automated systems (AKTA platform), depth-filtration and Tangential Flow Filtration operations
  • Demonstrated experience working in cross-functional teams
  • Experience with functional testing (PCR, LAMP, etc.) preferred
  • Experience with protein production at a range of scales preferred
  • Aptitude to work in a complex and rapidly growing company
  • Must possess excellent organizational, interpersonal, and problem solving skills
  • Demonstrated experience with development and implementation of new technologies and technical processes that improve the quality, efficiency, and/or productivity of products and/or laboratory services
  • Effective communication skills with technical staff, peers, and customers
  • Results-oriented, ensuring targets are met on time and on budget
  • Must demonstrate good professional judgment and reliability
  • Must be highly accurate and detail-oriented
  • Knowledge of Microsoft Office Products
How to Apply

Interested candidates should submit their resume to with Job #120420GW in the subject line.

About Our Organization

Lucigen discovers, manufactures, and commercializes molecular biology products used across the spectrum from basic research to molecular diagnostics, including point of care. Founded in Wisconsin in 1998, Lucigen built on the discovery of a novel thermostable DNA/RNA polymerase from the hot springs in Yellowstone. Today, the products and services developed at Lucigen enable life-science professionals to perform their research and testing more efficiently and effectively. The company has grown to manufacture and sell over 130 biomedical research products and services to customers worldwide. Core competencies include enzyme evolution, protein expression, cloning, competent cells, NGS, and molecular diagnostics.

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