Scientist, NGS - VelocImmune Next

Regeneron Pharmaceuticals
Job Location
777 Old Saw Mill River Road
Tarrytown, NY 10591
Commensurate to experience

Health insurance, annual bonuses, stock option, 401k match, Pay Time Off, tuition reimbursement, and more.

Job Description

Job ID: 5389BR

Location: Tarrytown, New York

Department: VelocImmune Next ( )

We are seeking a creative, self· motivated scientist to join the Technology and Discovery Centers of Regeneron Pharmaceutical Inc. in Tarrytown, NY. The successful candidate will support on-going, and initiate new, research projects towards generating, identifying, characterizing, and modifying novel antigen receptor molecules based on analyses of Next Generation Sequencing (NGS) data. The ideal candidate should have a strong combined background in computer science, immunology and molecular biology, as well as experience in bioinformatic analyses of NGS data from different sequencing platforms.

- Develop and refine programs to analyze NGS data on antigen receptor repertoire
- Automate NGS analysis on antigen receptor repertoire sequencing.
- Evaluate novel engineered mouse models based on NGS analysis.
- Extend analysis pipelines for BAC and L TVEC sequencing applications.
- Extend analysis pipelines for exome and whole genome sequencing applications of human
and mouse samples.
- Apply and develop computational methods to model and refine protein structures based on
available experimental data.
- Model protein interactions (e.g. antigen/receptor) using computational structural biology tools.
- Set up and follow collaborations within and outside the company to acquire structural data for proteins of interest.


This position requires a minimum of a  Ph.D degree in Bioinformatics, Computational Biology, Computer Science, Biomedical Engineering or related fields, with 1-3 years research experience analysis of NGS data. The candidate needs to be familiar with most up-to-date sequencing platforms (e.g. Iliumina Mi-seq, Hi-seq, Pac Bio, Ion torrent, etc). Solid knowledge of scripting languages (Perl, Python, R or Ruby), SQL and Unix OS are strictly required. The candidate should also understand basic lab technologies in molecular biology, especially for NGS sample preparation. Experience in computational structural biology is strongly preferred. Candidate should have good oral and written communication skills and a clear sense of organization, purpose, and accountability.

How to Apply

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.


About Our Organization

Regeneron Pharmaceuticals is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.

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