Scientist (Molecular Biologist) | GenomeWeb

Scientist (Molecular Biologist)

Organization
International Agency for Research on Cancer
Job Location
Lyon
France
Salary
Annual, net of tax: 59,308 euros at single rate; 63,232 euros with primary dependants
Benefits

IARC/WHO OFFERS AN ATTRACTIVE COMPENSATION PACKAGE INCLUDING AN ANNUAL NET SALARY (SUBJECT TO MANDATORY DEDUCTIONS FOR PENSION CONTRIBUTIONS AND HEALTH INSURANCE), DEPENDENCY BENEFITS, PENSION PLAN, HEALTH INSURANCE SCHEME, AND 30 DAYS ANNUAL LEAVE. BENEFITS FOR INTERNATIONALLY RECRUITED STAFF MAY INCLUDE TRAVEL AND REMOVAL EXPENSES ON APPOINTMENT AND SEPARATION, ASSIGNMENT GRANT, RENTAL SUBSIDY, AND HOME LEAVE.

Job Description

OBJECTIVES OF THE PROGRAMME The overarching objectives of the Molecular Mechanisms and Biomarkers Group (MMB), within the Mechanisms of Carcinogenesis Section (MCA), are (1) to generate evidence-base for cancer prevention, by identifying novel mechanisms of carcinogenesis involving cellular pathways deregulated by specific environmental and life-style risk factors; (2) to develop and validate biomarkers of exposure, cancer risk or detection, alongside methodologies and resources applicable to population-based studies coordinated by IARC and external collaborators. The MMB Group employs experimental and molecular epidemiology studies (using cell-lines as models and human cancer specimens, respectively) to elucidate molecular events and biological processes involved in critical steps of cancer development and progression. Important parts of its strategy are investigations of causal links between specific environmental exposures and (epi)genetic alterations, identified through own as well as major international cancer genomics efforts. Functional studies of molecular pathways related to mutagenesis, DNA damage response/repair, cell proliferation, survival and death, and their critical alterations by specific environmental carcinogens are conducted in in vitro perturbation models by advanced methods of molecular and cellular biology. Tumour tissues and nucleic acids from cancer patient body fluids are exploited as sources of informative biomarkers. These activities collectively aim to contribute to evidence-based cancer prevention strategies. Purpose of the Position: Under the supervision of the Head of the MMB Group, the incumbent conducts own and collaborative research studies in these areas: laboratory research investigations of molecular alterations and cellular pathways involved in cancer development and progression, and their relationship with known or suspected etiological factors; discovery and validation of molecular biomarkers in the context of case-control and population-based cancer research studies. Organizational Context: The incumbent conducts and drives expert laboratory research within MCA/MMB, participates in initiatives for international collaborations and to identify opportunities for collaborative and inter-disciplinary research. Initiative and considerable degree of independence in promoting collaborations across IARC groups/sections is expected, in line with the strategic goals set for MCA/MMB. He/she also assists the MMB Group Head and MCA Section Head in overseeing scientific projects and other relevant activities and provides expert assistance/advice on relevant research projects at IARC and those conducted with external networks. Description of Duties: Within the framework of the MCA/MMB activities and under the guidance of MMB Group Head, the incumbent actively contributes to these areas: 1) Develop and conduct state-of-the-art laboratory research projects to elucidate the molecular bases of cancer phenotypes and to discover/validate molecular biomarkers of carcinogen exposure, disease risk and detection. 2) Develop and apply advanced methods of molecular biology, such as (epi)genomic profiling, applicable to sources of specimens associated with human population-based studies (biobanks). 3) Prepare and write scientific manuscripts, expert reviews, and reports on mechanistic and profiling studies. 4) Contribute to writing and write own grants to attract research funding from competitive sources in the relevant research areas. 5) Seek and develop internal and external collaborations where advanced molecular biology approaches may add value to research projects. 6) Provide technical guidance and supervision to students, visitors and trainees hosted by the MCA Section. 7) Assist in the organization of various scientific and/or technical activities related to on-going and future studies in cancer biology. 8) Perform other relevant duties as assigned by the Supervisor.

Requirements

Education Essential: Advanced university degree - PhD (or MD) in molecular biology, genetics, genomics, cancer biology, or related field. Skills Applied knowledge in modern molecular/cell biology and genomics in particular, with respect to cancer research. Familiar with preparation of scientific manuscripts and grant applications. Good organization and communication skills. Required WHO competencies 1) Produce and deliver quality results. 2) Create an empowering and motivating environment. 3) Foster integration and teamwork. 4) Move forward in a changing environment. 5) Communicate in a credible and effective way. 6) Respect and promote individual and cultural differences. Experience Essential: At least two years of relevant professional experience in the field of cancer biology. Experience in molecular and cell biology related to cancer research. Experience in working with human specimens and in mechanistic/functional studies using cell cultures. Solid publication record in the relevant research area. Desirable: Experience at international level and in international research projects. Experience in molecular and genetic profiling, massively-parallel sequencing and related data analysis and interpretation will be an asset. Languages Excellent knowledge of English. Working knowledge of French would be an asset. Additional Information Please note that a list of publications is compulsory. To add this list, please go to your profile under additional information. Candidates called for interview may be expected to give a seminar.

How to Apply

Currently accepting applications Follow the appropriate application link at the bottom of this page: https://erecruit.who.int/public/hrd-cl-vac-view.asp?intra=1&jobinfo_uid_... This vacancy notice may be used to fill other similar positions at the same grade level. Online applications are strongly encouraged to enable WHO to store your profile in a permanent database. Please visit WHO's e-Recruitment website at: www.who.int/employment. The system provides instructions for online application procedures. All applicants are encouraged to apply online as soon as possible after the vacancy has been posted and well before the deadline stated in the vacancy announcement.

About Our Organization

WHO is committed to workforce diversity. Any appointment/extension of appointment is subject to WHO Staff Regulations, Staff Rules and Manual. Only candidates under serious consideration will be contacted.

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