Scientist I/II - Analytical

Job Location
Gaithersburg, MD 20878
Job Description

If you're inspired by the possibilities of science to change lives and you thrive when making brave decisions - join us.
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you'll have the opportunity to make a difference in people's lives every day. As one of the world's premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health, and help fight and cure disease.  As a Scientist I/II in Gaithersburg, MD you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives.
We're constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We're pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we're industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.


Main Duties and Responsibilities 
Medimmune has an opportunity for a Scientist I/II in the Analytical Sciences Department.  The successful candidate will be responsible for analytical method development and carry out detailed characterization of biopharmaceutical products, such as humanized monoclonal antibodies, antibody-drug conjugates, bispecific antibodies, recombinant proteins, mRNA using analytical tools.  She/he will also be responsible to support regulatory filings, as well as troubleshooting for projects in research and development. The candidate will work on complex and technically demanding projects where analysis of data requires an evaluation of multiple variables. The candidate will make detailed experimental observations, review and analyze data, and interpret experimental results.  The candidate will present scientific data to both internal audiences within the company and external scientific colleagues.  The ability to follow SOPs, policies, and regulations, and to perform routine lab equipment maintenance is required.  As the position will require constant collaborative interactions with co-workers across functional groups, he/she must be able to work in a matrix structure and interface with different groups within research and development.
Essential Requirements 
The candidate must have deep understanding and expertise in several of the following technique categories: mass spectrometry (intact mass, peptide map, disulfide mapping, 2D-LC/MS), chromatography (SEC, IEC, RP, HILIC(Glycan), HIC), electrophoresis (icIEF, CE-SDS), and other analytical technologies (UV, ELISA, Western Blot, WES, SDS-PAGE, 2D-Gel)
In addition, broad background on protein structure characterization is essential. Prefer the candidate has both early and late stage experience.
Excellent teamwork and communication skills, including good documentation and excellent writing skills with publications, are critical. Good multi-tasking, time management and organizational skills are essential. Strong verbal and written communication skills are essential.
Education :     
MS or Ph.D. in Biophysics /Chemistry or a related field.         
Experience : 
With MS degree, 8-15 years' experience; with Ph.D. degree, 0-6 years' experience. Experience in an industrial analytical lab working with therapeutic proteins are desirable.
Desirable Requirements 
Previous GLP and/or cGMP experience is desirable.
Experience with method qualification/validation is desirable. Experience in GMP lab is huge plus. Supervisory, time/project management, and regulatory filing experience are desirable. 
Next Steps - Apply today! 
To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience - it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity.  If you know someone who would be a great fit, please share this posting with them.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised. 

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