Scientist I/II

Two Pore Guys
Job Location
2161 Delaware Ave
Suite B
Santa Cruz, CA 95060
Job Description


We are seeking a highly motivated Scientist to join the Biochemistry group at TPG. The Scientist will be responsible for creating, executing, and managing molecular biology and biochemical experiments, and developing analytical methods that support the characterization of biomolecules. The incumbent will perform established assays, develop new assays, manage projects, analyze data, create reports, and manage research associates.


  • Devise and perform a wide range of assays using molecular biology, analytical biochemistry and other laboratory testing procedures to achieve specific project goals and broader strategic objectives. Techniques include biomolecule labeling and chemical modification, electrophoretic mobility shift assays, PCR, qPCR, ddPCR, isothermal amplification (LAMP, HDA, SDA), along with other standard molecular biology techniques

  • Create bioconjugates and develop purification methods, both analytical and preparative, to purify those molecules.

  • Develop methods to characterize biomolecular conjugates and work with core facilities to employ characterization assays

  • Assist in generating written material including patents, grants, reports, and scientific publications

  • Troubleshoot reagent and assay development activities by referencing published literature and through discussions with the supervisor and laboratory personnel

  • Maintain timely and accurate documentation of all laboratory activities in a lab notebook or electronic notebook

  • Use spreadsheet, word processing, and other data analysis software to analyze data and produce accurate, concise data summaries.

  • Prepare written and oral reports for presentation to the supervisor(s) and at departmental or outside meetings

  • Exercise technical discretion in the design, execution and interpretation of experiments that contribute to project strategies within defined parameters

  • Perform additional job related duties as required 


  • Requires a PhD degree in Chemistry, Biochemistry, Biology or related field. Additional postdoctoral or industry experience is desired. Compensation will scale with experience and expertise.

  • Strong work ethic, attention to detail, ability to maintain accurate records

  • Strong critical thinking, time management and organizational skills.

  • Demonstrated ability to manage and prioritize multiple tasks and consistently meet deadlines

  • Ability to troubleshoot within scope of training

  • Excellent written and verbal communication skills. Ability to communicate

    effectively with others.

  • Ability to work effectively both independently and as a member of a team.

  • Flexibility in work schedule to meet business needs.


  • Industry experience in the molecular diagnostics field (analyte or nucleic acid testing)

  • Expertise in qPCR, ddPCR, isothermal amplification & allele-specific detection techniques

  • Prior experience with portable (handheld) amplification hardware

  • Expertise in creating molecular conjugates, drug conjugates, chemical

    coupling techniques and proofing said molecules

  • Experience with HPLC and Mass Spectrometry

  • Experience with surface modification chemistries for a number of

    applications, including preventing non-specific molecular interactions and

    bead labeling

  • Facility with tools for bioinformatics, data analysis & programming 

How to Apply

Email resume and cover letter to [email protected]

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