Scientist I, Antibody Discovery and Engineering - Developability

Job Location
Gaithersburg, MD
Job Description

We are seeking a highly motivated individual to join our antibody engineering and technology development effort in the Department of Antibody Discovery & Protein Engineering, supporting MedImmune's therapeutic antibody programs. The major responsibilities of this position are to participate in and drive efforts towards optimizing antibodies and other protein therapeutics, and to contribute to new technology platform development and pipeline implementation. 

Education Requirements: 

PhD with 0-3years experience 

MS with 3-6years experience 

BS with 5-8years experience 
The candidate will be responsible for one or more of the following tasks: antibody discovery and engineering, screening antibody libraries, developing and performing primary screening assays, recombinant expression and purification of antibodies/proteins, and epitope characterization of candidate antibodies. Experience with Developability screens of therapeutic proteins preferred. Applicants with considerable experience in protein/antibody engineering, display technologies (phage, mammalian, or yeast surface display), and/or structural biology will be at an advantage. The successful candidate will be independent, creative, and have a track of record of research accomplishments in the various molecular and structural aspects of protein design. Strong interpersonal and oral/written communication skills are essential. 
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled/Sexual Orientation Additional Notes 
The ideal candidate will have proven technical proficiency in most of the following areas: 
- molecular biology, in particular site-directed mutagenesis/cloning/PCR, protein libraries design and construction, directed evolution 
- high throughput screening 
- assay development 
-expression of recombinant proteins in bacterial and mammalian cells 
- protein purification 
- biophysical characterization as it pertains to Developability 
Good oral and written communication skills, and the ability to work independently and as a part of a team are needed. Must be a team player with excellent communication and interpersonal skills. Experience with automation and high throughput screening is a plus. 
Req ID 10337 Position Category Research - Antibody Development & Protein Engineering


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