Scientist - Clinical Diagnostics Development

Job Location
San Diego, CA 92121
competitive salary, bonus, equity

full benefits package, effective hire date

Job Description

As a member of the Clinical Diagnostics Development team, the Scientist will plan and execute development projects leading to Laboratory Developed Tests utilizing next-generation sequencing and mass spectrometry.  The ideal candidate will possess extensive knowledge of biochemistry and molecular biology with experience in generating and optimizing nucleic acid detection assays.  Previous experience performing statistical data analysis with R or JMP is preferred.  Please note, this is a Development role and not with the R&D department. 



  • Design, develop and optimize diagnostic assays, execute experimental protocols, and process data for quantitative review
  • Develop and transfer laboratory methods to a production environment
  • Participate in verification studies in support of laboratory developed tests
  • Utilize cutting edge technologies to develop high quality laboratory developed tests
  • Perform data analysis with graphical representations of findings using appropriate software (R, JMP, Excel)
  • Create appropriate model systems for proof-of-concept, feasibility,  and validation studies
  • Document all work in the form of laboratory notebook, study reports and summary reports
  • Present data clearly and concisely at departmental meetings and project meetings
  • Participate and present findings at conferences
  • Publish scientifically relevant data in peer reviewed journals
  • Participate in development of patent applications, if applicable
  • PhD in Molecular Biology/Biochemistry/Genetics or related field with 3+ years’ experience in an applied research and/or development environment (Postdoctoral work may serve as experience) or Masters in Molecular Biology/Biochemistry with 5+ years research experience in an applied research and/or development environment
  • Significant experience with molecular biology techniques required
  • Expertise in genomics/genetics with regards to sequence manipulation, assay design and assay performance optimization
  • Strong background in experimental design, using DOE for assay optimization
  • Strong background in data analysis using statistical software packages including R or JMP
  • Hands-on experience with qPCR and next-generation sequencing technologies is desired
  • Experience with assay/test development/submission and documentation for 510k or IVD is a plus


Sequenom is an EOE - Minority/Female/Disability/Vets


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About Our Organization

Sequenom Laboratories, a wholly-owned subsidiary of Sequenom, Inc., is a CAP accredited and CLIA-certified molecular diagnostics laboratory, dedicated to the development and commercialization of laboratory-developed tests (LDTs) for prenatal and ophthalmic diseases and conditions.

As a life sciences company, Sequenom (NASDAQ: SQNM) has a guiding vision: To improve healthcare by providing revolutionary genomic and genetic analysis solutions for the clinical research and molecular diagnostic markets.

What makes this vision a reality? Our deep commitment to "Quality of Science." For us, only the highest quality is acceptable. Sequenom team members thrive in a "science first" environment where ideas and innovation are part of daily life. This is your opportunity to work on cutting-edge science that is revolutionizing patient care.

Our innovation-driven culture means life at Sequenom is fast-paced, dynamic, and fun with rewarding benefits and performance rewards. With a clear vision for the future, all employees have the opportunity to make a difference and are encouraged to share new ideas. We foster a collaborative work environment and encourage curiosity at all levels.  Our corporate headquarters is located in the heart of San Diego’s life sciences community, less than a mile from the beach.

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