Scientist, Bioinformatics (Molecular Profiling - Immuno-Oncology)

Regeneron Pharmaceuticals
Job Location
777 Old Saw Mill River Road
Tarrytown, NY 10591

Health insurance, annual bonuses, stock option, 401k match, Pay Time Off, tuition reimbursement, and more.

Job Description

- Collaborate with Immuno-Oncology (I/O) scientists in preclinical and clinical departments to design profiling experiments and draft data analysis plan
- Communicate results with I/O scientists, refine analysis based on feedback, and plan/prioritize follow-up experiments
- Prepare clear, concise and easy-to-understand presentations and documentations for collaborators, senior management and government agencies
- Analyze proprietary and public profiling data to support I/O targets and biomarker discovery
- Analyze proprietary tox profiling data to support Tox studies
- Analyze proprietary clinical profiling data to support Clinical studies
- Contribute to team effort of developing I/O data analysis strategies and establishing I/O data analysis best practices
- Participate in team effort of organizing and integrating proprietary and public molecular profiling data to enable data sharing and visualization for bench scientists


This position requires a minimum of a PhD in a related field, and preferably 2+ years postdoctoral experience.  Additional requirements include, but are not limited to:
- Expertise in immuno-oncology
- Expertise in NGS data analysis to detect gene expression, variants, copy number variation, fusion and alternative splicing
- Strong preference for R power users, especially DeSeq 6+
- Strong preference for experience in Single Cell Sequencing
- Experience with analyzing cancer profiling data in the public domain such as TCGA
- Experience with a variety of molecular profiling platforms such as microarray and NGS, and their data analysis best practices
- Familiarity with TCR repertoire sequence analysis, antigen prediction, modeling (e.g., machine learning) and network building (e.g. gene regulation networks): Keen interest and determination to be at the cutting-edge of algorithms and model building
- Familiarity with bioinformatics tools and software such as R/Matlab, Linux, Perl, Python, Ruby, Java, Ruby on Rails, SQL, web programming
- Ability to work both independently and collaboratively
- Team spirit and commitment to share and collaborate
- Excellent communication and presentation skills

Preferred skills:
- Experience with Structural and Computational Biology and Bioluminate is a plus

How to Apply

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry.  Visit todayat and search " 6284BR " to apply.

About Our Organization

Regeneron Pharmaceuticals is a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron commercializes medicines for eye diseases, high LDL-cholesterol, and a rare inflammatory condition and has product candidates in development in other areas of high unmet medical need, including oncology, rheumatoid arthritis, asthma, atopic dermatitis, pain, and infectious diseases.

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