Research Technician III - Metastatic Microenvironments

Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance
Job Location
Seattle, WA
Job Description

Cures Start Here.
Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch's five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children's, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest.

Careers Start Here.
A research technician position (full-time) is immediately available in a newly established laboratory within Fred Hutchinson Cancer Research Center's Translational Research Program. The Laboratory for the Study of Metastatic Microenvironments focuses on understanding the biology underlying disseminated tumor cell (DTC) dormancy and formulating therapeutic means to eradicate dormant DTCs.

We are looking for a dynamic, organized, and highly motivated individual who will be responsible for performing standard and investigative laboratory work in support of scientific research by conducting cell culture experiments, working with murine models, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; performing calculations; and preparing charts, graphs and both written and visual summaries.

This position will work under the Principal Investigator and work with the laboratory personnel. The individual will use discretion and judgment in carrying out the following job duties:
- Manage a murine colony, including breeding, genotyping, and weaning litters, as well as live imaging and techniques associated with tumor xenograft experiments.
- Perform experiments at the bench level to support investigative work. This will involve two- and three-dimensional cell culture, live cell imaging, immunofluorescent staining, tissue sectioning, plasmid preparation, cloning, retro- and lenti-virus production, and immunoblotting.
- Prepare and maintain laboratory reagents, stocks, cultures or cell lines.
- Perform and modify documented protocols and assays.
- Maintain laboratory records and compile data on experiments and assays.
- Interpret and report experimental results.
- Perform statistical analysis of test results and prepare written reports on work performed.
- Operate and carry out basic maintenance of laboratory equipment.
- Order and maintain appropriate levels of supplies.
- Identify methodological problems in research protocol and implement modifications to optimize experimental results.
- Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
- Assist in the design of experiments; may be responsible for the performance of individual research projects.
- Conduct literature reviews to assist in determining most suitable methods to be used in research.
- Assist in publication of results by proofreading, editing, and contributing ideas.
- May perform statistical analyses, write computer programs, or manage research database.
- Perform other duties as required.

A bachelor's degree in the biological sciences and at least five years experience in basic laboratory skills are required, including experience with murine models and cell culture. Independent research experience outside of laboratory course work is strongly desired. The ideal candidate will be well-organized, pay exquisite attention to detail, have demonstrated proficiency in independently running pre-clinical trials, skilled in collecting and analyzing data (e.g., SigmaPlot), and adept in establishing and managing lab databases (Google Sheets, MS Excel).

To apply for this position, please CLICK HERE

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