Research Technician III

Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance
Job Location
Seattle, WA
Job Description

Fred Hutchinson Cancer Research Center, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, the Center's four scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Hutchinson Center, in collaboration with its clinical and research partners, the University of Washington and Children's Hospital and Regional Medical Center, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Join us and make a difference.

The HIV Vaccine Trials Network (HVTN) Laboratory Center is part of an international collaboration of scientists and educators searching for effective and safe vaccines. The HVTN's mission is to facilitate the process of testing preventive vaccines against HIV/AIDS and related infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The Laboratory Center is responsible for carrying out the scientific agenda of the HVTN by conducting laboratory based studies to evaluate the immunogenicity of investigational vaccines.

This role will report to HVTN project manger under the direction of the Principal Investigator or higher-level laboratory personnel. Extensive flow cytometry experience as well as specialized laboratory skills and knowledge are applied in fulfilling complex research responsibilities. Discretion and judgment are used in the performance of daily duties.

- Directly execute the implementation of experiment plans and analysis. Must work up an experiment plan, ensure other technicians also working on the project are properly trained (as applicable) assist in analysis, and provide a report with data interpretation to the project manager.
- Responsible for independent work-up and performance of new assays, including literature reviews, experimental design, optimization, troubleshooting, analysis and reporting results.
- Identify methodological problems in research protocol and implement modifications to optimize experimental results
- Transfer newly developed assays and technologies to other parts of the lab and train lab members to be proficient in them.
- Assists lab members and collaborators in training with assay protocols, flow cytometry panel design, complex data analysis in FlowJo and JMP.
- Directly execute experiment plans and analysis, which includes but is not limited to: creation of an experiment plan, training of technicians (as applicable), completion of laboratory assays, analysis of data, and production of reports with data interpretation to present to the project manager.
- Provides independent development of new assays, including literature reviews, experimental design, optimization, troubleshooting, analysis and reporting results.
- Transfers newly-developed assays and technologies to other parts of the lab and train lab members to be proficient in those assays.
- Assists with production of manuscripts by taking part in writing, data analysis, figure creation, and interpretation of results.
- Provides support in the design, writing and review of HVTN study plans.
- Prepares and presents written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
- Performs data management and statistical analyses, and manages research databases.
- Other duties as assigned.

Intermediate level position requiring 5-8 years previous experience working in laboratory. MA/MS or BA/BS degree required with preference for biochemistry, immunology or similar areas of focus. Experience with immunology, cellular immunologic assays, tissue culture, microscopy, PCR, DNA extractions, and micropipetting are preferred. Experience in a GLP setting or clinical experience, such as CLIA, CAP, or JACHO, with strong documentation skills is also desirable. Motivation and adaptability and ability to be a strong team player are essential, as is a keen interest in the HIV vaccine field. Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including HIV-1) and to work some evenings and weekends.

If interested, please apply online at

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