Cures Start Here.
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network.
Careers Start Here.
The HIV Vaccine Trials Network (HVTN) Laboratory Center is part of an international collaboration of scientists and educators searching for effective and safe vaccines. The HVTN's mission is to facilitate the process of testing preventive vaccines against HIV/AIDS and related infectious diseases. The organization conducts all phases of clinical trials from evaluating experimental vaccines for safety and the ability to stimulate immune responses through to testing vaccine efficacy. The Laboratory Center is responsible for carrying out the scientific agenda of the HVTN by conducting laboratory-based studies to evaluate the immunogenicity of investigational vaccines.
Reports to Staff Scientist or higher-level laboratory personnel. Performs and leads complex research assays utilizing extensive flow cytometry experience as well as specialized immunology, molecular biology and bioinformatic laboratory skills in the pursuit of evaluating vaccine-induced immune responses. Discretion and judgment are used in the performance of daily duties.
1. Directly execute and drive the implementation of immunological experimental assays.
2. Must write up an experiment plan, perform and lead experiments, assist in analysis, and provide a report with data interpretation.
3. Lead and train other technicians, or team members.
4. Responsible for independent work-up and performance of new assays, including literature reviews, experimental design, optimization, troubleshooting, analysis and reporting results.
5. Transfer newly developed assays and technologies to other parts of the lab.
6. Assist in the design of experiments; may be responsible for the performance of individual research projects.
7. Conduct literature reviews to assist in determining most suitable methods to be used in research.
8. Identify methodological problems in research protocol and implement modifications to optimize experimental results.
9. Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
10. May perform statistical analyses, write computer programs, or manage research data base.
11. Other duties as assigned.
Intermediate level position requiring 4-6 years previous experience working in a research laboratory. MA/MS or BA/BS degree required with preference for biochemistry, immunology or similar areas of focus. Experience with HIV/AIDS or other infectious diseases (such as TB and malaria), cellular immunologic assays, tissue culture, flow cytometry, molecular biology, and bioinformatics, strongly desired. Motivation, adaptability and ability to be a strong team player are essential, as is a keen interest in the HIV vaccine field. Applicants must be willing to work with biohazardous/infectious agents (e.g., bloodborne pathogens, including HIV-1) and to work some evenings and weekends.
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