Research Technician - Chromatin and Epigenetic Regulation

Van Andel Research Institute
Job Location
333 Bostwick NE
Grand Rapids, MI 49503

This is a full-time opportunity and this individual will be eligible to participate in our comphrensive benefits, which include:

- Medical, Dental, and Vision

- Employer sponsored life and AD&D insurance

- Additional voluntary life and AD&D insurance for employees and dependents

- Short-term and long-term disability insurance

- Flexible spending accounts for health and child/elder care

- 401k Retirement 

- Paid vacation, holidays, and personal days


Job Description

This position is available for a motivated full time Research Technician in the Van Andel Research Institute’s Laboratory of Chromatin and Epigenetic Regulation. Under the direction of Dr. Scott Rothbart, the lab studies basic molecular and cellular mechanisms controlling chromatin accessibility, interaction and function. Positioned in the VARI Center for Epigenetics, the candidate will be engrossed in an energetic, interactive and fast-paced environment at the forefront of research into epigenetic mechanisms and therapeutics in human health and disease.



The chosen candidate will assist senior personnel with experiments and lab operations, and will be expected to participate actively in experimental planning and execution, as well as data analysis and presentation. The candidate will also have the opportunity to conduct independent research projects and author on scientific publications.


The position will require an individual to be responsible for the following minimal tasks:

Ø  Maintain and manipulate mammalian cell lines with good sterile technique

Ø  Perform molecular biology experiments including cloning, PCR, mutagenesis and DNA analysis

Ø  Express and purify recombinant proteins from bacteria

Ø  Analyze proteins by SDS-PAGE and western blotting

Ø  Prepare buffers, solutions, reagents, media and stains necessary for experimental procedures

Ø  Inventory laboratory supplies and equipment and prepare requisitions for approval

Ø  Perform other laboratory duties as requested


Additional skills that are desired, but not required:

Ø  Experience with biophysical assays (e.g., fluorescence polarization and isothermal titration calorimetry)

Ø  Proficiency in techniques to analyze DNA methylation and histone post-translational modifications

Ø  Familiarity with sample preparation for mass-spec based proteomics


Ø  Experience with fabrication and/or use of microarrays


Ø  A B.Sc. degree (or equivalent) in biological sciences. An M.S. degree in biochemistry, molecular and cell biology or related fields is preferred.

Ø  At least 2-5 years of biological science related experience at the lab bench


Ø  Proficiency with computers and Microsoft Office (Word, Excel, PowerPoint)

How to Apply

Interested candidates should submit the following items as a single combined PDF file through our online submission system by visiting: 


1. A brief cover letter outlining your background, research interests, future plans, and how these factors fit with the current research in the Laboratory of Chromatin and Epigenetic Regulation.


2. A curriculum vitae.



3. A list of 3 individuals and their contact information that have agreed to act as referees.

About Our Organization

Van Andel Institute (VAI) conducts biomedical research, with a focus on cancer and Parkinson’s disease and also emphasizes translating scientific research results into clinical applications. VAI is located in downtown Grand Rapids, Michigan, and is acknowledged as one of the leading independent research institutes expanding the life science industry in this region. Collaborative partnerships among world-class health care, research, and educational organizations have led to dramatic growth in the life sciences sector in the region, making Grand Rapids a career destination choice in this area.

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